Role of Nonproteolytically Activated Prorenin in Pathologic, but Not Physiologic, Retinal Neovascularization [PDF]
Recently, it was revealed that the inhibition of nonproteolytic activation of prorenin led to significant suppression of ocular inflammation in endotoxin-induced uveitis. The purpose of the present study was to investigate whether nonproteolytically activated prorenin plays a role in ischemia-induced retinal neovascularization.C57BL/6 neonatal mice ...
Shingo, Satofuka +11 more
openaire +3 more sources
Vaginal rejuvenation using energy-based devices [PDF]
Physiologic changes in a woman’s life, such as childbirth, weight fluctuations, and hormonal changes due to aging and menopause, may alter the laxity of the vaginal canal, damage the pelvic floor, and devitalize the mucosal tone of the vaginal wall ...
Cheryl Karcher, MD, Neil Sadick, MD
doaj +2 more sources
Hepatocyte Transplantation in the Treatment of Acute Liver Failure: Microencapsulated Hepatocytes versus Hepatocytes Attached to an Autologous Biomatrix [PDF]
A liver transplant is considered today to be the only effective therapeutic solution for many otherwise intractable hepatic disorders. However, liver transplantation is beset by shortage of donors.
Giovanni Ambrosino M.D. +12 more
doaj +2 more sources
Fibrin glue-assisted for the treatment of corneal perforationsusing glycerin-cryopreserved corneal tissue [PDF]
AIM: To evaluate the outcomes and safety of lamellar keratoplasty (LK) assisted by fibrin glue in corneal perforations.METHODS: Six eyes of 6 patients affected by different corneal pathologies (2 posttraumatic corneal scar and 3 bacterial keratitis ...
Nuo Dong +5 more
doaj +2 more sources
Emerging nonsurgical methods for the treatment of vitreomacular adhesion: a review [PDF]
Eric W Schneider, Mark W JohnsonDepartment of Ophthalmology and Visual Sciences, University of Michigan, WK Kellogg Eye Center, Ann Arbor, MI, USAAbstract: With the dissemination of optical coherence tomography over the past two decades, the role of ...
Schneider EW, Johnson MW
doaj +1 more source
DHF does not affect physiologic revascularization or pathologic neovascularization at P17. [PDF]
Panel A, DHF treatment schedule. DHF was injected daily from P6 until P16, and eyes were collected at P17. Animals were exposed to 75% oxygen from P7-P12 then kept at room-air conditions until P17.
Ismail S. Zaitoun (11561584) +5 more
core +1 more source
Physiologic MR imaging of the tumor microenvironment revealed switching of metabolic phenotype upon recurrence of glioblastoma in humans [PDF]
Treating recurrent glioblastoma (GB) is one of the challenges in modern neurooncology. Hypoxia, neovascularization, and energy metabolism are of crucial importance for therapy failure and recurrence.
Stadlbauer, Andreas +8 more
core +2 more sources
Circulating angiogenic cells in glioblastoma: Toward defining crucial functional differences in CAC-induced neoplastic versus reactive neovascularization [PDF]
Background: In order to identify suitable therapeutic targets for glioma anti-angiogenic therapy, the process of neovascularization mediated by circulating angiogenic cells (CACs) needs to be scrutinized.
Dik, Wim +8 more
core +1 more source
Metabolic Tumor Microenvironment Characterization of Contrast Enhancing Brain Tumors Using Physiologic MRI [PDF]
The tumor microenvironment is a critical regulator of cancer development and progression as well as treatment response and resistance in brain neoplasms.
Max Zimmermann +7 more
core +1 more source
Toward the Clinical Application of Therapeutic Angiogenesis Against Pediatric Ischemic Retinopathy
Therapeutic angiogenesis refers to strategies of inducing angiogenesis to treat diseases involving ischemic conditions. Historically, most attempts and achievements have been related to coronary and peripheral artery diseases.
Dong Hyun Jo, Jeong Hun Kim
doaj +1 more source

