Results 1 to 10 of about 1,442,388 (221)

Developing a strain-dependent susceptibility to hepatocellular carcinoma in a murine model based on histopathological evidence and genetic context. [PDF]

Animal Model Exp Med
Using F1 (C57BL/6J/Smad4+/− X CC) mice, we found that partial loss of Smad4 promotes liver carcinogenesis in a strain‐dependent manner, highlighting the importance of genetic modifiers in tumor susceptibility. The use of Collaborative Cross mice provides a valuable platform for uncovering genotype‐specific cancer susceptibilities in preclinical ...
Zohud O, Nashef A, Abu-Elnaaj I, Iraqi FA.   +3 more
europepmc   +2 more sources

The susceptibility to weight gain in male C57BL/6 mice fed high-fat diet is due to a small set of genes predominantly not expressed in the brain. [PDF]

Proc Natl Acad Sci U S A
Wu Y, Rudolf AM, Wang L, Zhang Z, Niu C, Xia F, Li M, Wang A, Derous D, Mitchell SE, Zhang H, He Y, Speakman JR.   +12 more
europepmc   +1 more source

Genetically diverse CC and DO mouse models enable comprehensive assessments of novel tuberculosis vaccines. [PDF]

NPJ Vaccines
Lai R, Kurtz SL, Gould V, Tran A, Afkhami S, Brosch R, Lindestam Arlehamn CS, Xing Z, Elkins KL, Behar SM.   +9 more
europepmc   +1 more source

Impact of Probiotic Intervention on Lymphocyte Activity in Mice Challenged with Pea Albumins (<i>Pisum sativum</i> L.). [PDF]

Nutrients
Chudzik-Kozłowska J, Wasilewska E, Mikołajczyk A, Złotkowska D.   +3 more
europepmc   +1 more source

Preclinical Evaluation of the SMNP-Adjuvanted R21 Malaria Vaccine Across Multiple Mouse Strains. [PDF]

Vaccines (Basel)
Turan G, Fedorova K, Hill AVS, Salman AM.   +3 more
europepmc   +1 more source

Analysis of energy expenditure and behavioral characteristics in different mouse strains under normal and disease conditions. [PDF]

Animal Model Exp Med
Zeng J, Ji Y, Zou Y, Tan J, Wu T, Shen C, Huang T, Xiong S, Liu M, Yang M, Lai J, Ma J, Wan J, Fu X, Qian J, Li H, Yuan L, Cai W.   +17 more
europepmc   +1 more source

Validation of targets linked to weight gain in C57BL/6 mice and translational aspects in humans. [PDF]

Proc Natl Acad Sci U S A
Wu Y, Rudolf AM, Wang L, Zhang Z, Niu C, Xia F, Li M, Wang A, Mitchell SE, Zhang H, He Y, Chen C, Speakman JR.   +12 more
europepmc   +1 more source

Strain-Dependent Network Activity Differences Underlie Social Decision-Making in Male Mice. [PDF]

eNeuro
Illescas-Huerta E, Villamizar A, Cum M, Padilla-Coreano N.   +3 more
europepmc   +1 more source

Genetic context shapes interpretation of AIRE and Notch4 in alopecia areata. [PDF]

JID Innov
Hobbs RP.
europepmc   +1 more source

Lethal C57BL/6 mouse model for Yezo virus infection and antiviral therapeutic evaluation. [PDF]

Emerg Microbes Infect
Liu Y, Liu N, Zhang G, Liu Z, Ji T, Li L, Wang Z.   +6 more
europepmc   +1 more source