Inter-individual Variability for High Fat Diet Consumption in Inbred C57BL/6 Mice [PDF]
Frontiers in Nutrition, 2019 Since inbred C57BL/6 mice are known to show inter-individual phenotypic variability for some traits, we tested the hypothesis that inbred C57BL/6 mice display a different tendency to consume a high fat (HF) diet.
Pablo N De Francesco +2 more
exaly +10 more sources
Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice [PDF]
BMC Neuroscience, 2001 Background The presynaptic protein α-synuclein is involved in a range of neurodegenerative diseases. Here we analyze potential compensatory mechanisms in α-synuclein null mutant mice.
Schoepfer Ralf, Specht Christian G
doaj +5 more sources
Mixed genetic background better recapitulates developmental and psychiatric phenotypes and heterogeneity than inbred C57BL/6J mice [PDF]
Scientific ReportsPreclinical models of neurodevelopmental and psychiatric conditions often rely on inbred mouse strains like C57BL/6J (B6), which exhibit limited genetic and behavioral variability.
Ana Dudas +6 more
doaj +3 more sources
Susceptibility and transcriptional characteristics of inbred C57BL/6J and outbred ICR mice in CDAHFD-induced MASH models [PDF]
Laboratory Animal ResearchBackground Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive fibrotic liver disease, the underlying mechanisms of which have not been fully elucidated.
Jing Zhou +9 more
doaj +2 more sources
Variation in the cortical area map of C57BL/6J and DBA/2J inbred mice predicts strain identity
BMC Neuroscience, 2005 Background Recent discoveries suggest that arealization of the mammalian cortical sheet develops in a manner consonant with principles established for embryonic patterning of the body.
Wu Fangbai +4 more
doaj +2 more sources
Shortcoming of the Mouse Model of Postoperative Ileus: Small Intestinal Lengths Have Similar Variations in In- and Outbred Mice and Cannot Be Predicted by Allometric Parameters [PDF]
BiomedicinesBackground/Objectives: The mouse model of postoperative ileus separates the gastrointestinal tract into 15 sections, 10 of which are in the small intestine, to measure intestinal transit time.
Maximiliane von Stumberg +3 more
doaj +2 more sources
Identification of vacuolar autophagic aggregates in the skeletal muscles of inbred C57BL/6NCrl mice
Laboratory Animals, 2023 A comprehensive pathological analysis of inbred strains is essential to define strain-specific spontaneous lesions and to understand whether a specific phenotype results from experimental intervention or reflects a naturally occurring disease. This study
Piegari G. +10 more
core +7 more sources
PLoS ONE, 2014 We generated C57BL/6NTac mice carrying a tyrosinase loss-of function mutation and a reversion of the nonagouti locus to agouti. This strain has a high superovulation response, allows visual detection of chimeric coat color contribution of C57BL/6 ES ...
Branko Zevnik +5 more
doaj +2 more sources
Interfrontal Bone Among Inbred Strains of Mice and QTL Mapping [PDF]
Frontiers in Genetics, 2019 The interfrontal bone (IF) is a minor skeletal trait residing between the frontal bones. IF is considered a quasi-continuous trait. Genetic and environmental factors appear to play roles in its development. The mechanism(s) underlying IF bone development
Heather Zimmerman +4 more
doaj +2 more sources
Consistent individual differences in some behaviors in mice of the C57Bl/6J inbred strain [PDF]
Anuario de Psicología, 2016 Los ratones de la cepa consanguínea C57Bl/6J muestran una considerable variación entre ellos en las conductas de deambulación, incorporación, aseo, y defecación en el campo abierto (coeficientes de variación entre 30% y 150%).
Vidal-Gómez, José, Vidal Gómez, José
core +4 more sources