Results 41 to 50 of about 1,442,388 (221)

Characterization of the acute inflammatory profile and resolution of airway inflammation after Igf1r-gene targeting in a murine model of HDM-induced asthma. [PDF]

PLoS ONE, 2017
Asthma is a chronic inflammatory disease characterized by bronchial hyperresponsiveness, mucus overproduction and airway remodeling. Notably, we have recently demonstrated that insulin-like growth factor 1 receptor (IGF1R) deficiency in mice attenuates ...
Sergio Piñeiro-Hermida, Elvira Alfaro-Arnedo, Joshua A Gregory, Raquel Torrens, Carlos Ruíz-Martínez, Mikael Adner, Icíar P López, José G Pichel   +7 more
doaj   +1 more source

Dose-dependent effects of dietary fat on development of obesity in relation to intestinal differential gene expression in C57BL/6J mice [PDF]

, 2011
Excessive intake of dietary fat is known to be a contributing factor in the development of obesity. In this study, we determined the dose-dependent effects of dietary fat on the development of this metabolic condition with a focus on changes in gene ...
Boekschoten, Mark V., Bachmair, Eva-Maria, Eva-Maria Bachmair, Isabel Rubio-Aliaga, Rubio-Aliaga Isabel, de Wit Nicole J. W., de Wit, Nicole J. W., Rubio-Aliaga, I., Nicole J. W. de Wit, Philip J. de Groot, Machmair, E.M., Boekschoten Mark V., Wit, N.J.W., de, Philip J de Groot, de Groot Philip J., Boekschoten, M.V., Muller, M.R., Daniel Hannelore, Hooiveld, Guido J. E. J., Rubio-Aliaga, Isabel, Müller, Michael, Nicole J W de Wit, Guido J E J Hooiveld, Hannelore Daniel, Müller Michael, Daniel, H., Mark V Boekschoten, Michael Müller, Hooiveld Guido J. E. J., de Groot, Philip J., Guido J. E. J. Hooiveld, Bachmair Eva-Maria, Daniel, Hannelore, Groot, P.J., de, Mark V. Boekschoten, Hooiveld, G.J.E.J., de Wit, Nicole J. W.;Boekschoten, Mark V.;Bachmair, Eva-Maria;Hooiveld, Guido J. E. J.;de Groot, Philip J.;Rubio-Aliaga, Isabel;Daniel, Hannelore;Müller, Michael   +36 more
core   +2 more sources

Stimulus Complexity and Mouse Strain Drive Escalation of Operant Sensation Seeking Within and Across Sessions in C57BL/6J and DBA/2J Mice

Frontiers in Behavioral Neuroscience, 2020
Sensation seeking is a heritable trait that is genetically correlated with substance use; the shared genetic mechanisms underlying these traits are largely unknown.
Price E. Dickson, Guy Mittleman
doaj   +1 more source

Genetic and morphometric characteristics of Korean wild mice (KWM/Hym) captured at Chuncheon, South Korea

Laboratory Animal Research, 2018
Laboratory inbred mice are used widely and commonly in biomedical research, but inbred mice do not have a big enough gene pool for the research. In this study, genetic and morphometric analyses were performed to obtain data on the characteristics of a ...
Hajin Nam, Yoo Yeon Kim, Boyoung Kim, Won Kee Yoon, Hyoung-Chin Kim, Jun Gyo Suh   +5 more
doaj   +1 more source

Compensatory role of C3 convertase on the strain difference for C3 protein expression in FVB/N, C3H/HeN and C57BL/6N mice

Laboratory Animal Research, 2020
To investigate the role of complement C3 (C3) convertase on the strain difference for C3 protein expression in three inbred mice strains, we compared the levels of C2, C3 and C4 mRNA, as well as C3 protein and C3 convertase activity in the serum and ...
Ji Won Park, Ji Eun Kim, Mi Ju Kang, Hyeon Jun Choi, Su Ji Bae, Dae Youn Hwang   +5 more
doaj   +1 more source

Helminth Parasites of Conventionally Maintained Laboratory Mice: II- Inbred Strains with an Adaptation of the Anal Swab Technique

Memorias do Instituto Oswaldo Cruz, 1998
Worm burdens recovered from inbred mice strains, namely C57Bl/6, C57Bl/10, CBA, BALB/c, DBA/2 and C3H/He, conventionally maintained in two institutional animal houses in the State of Rio de Janeiro, RJ, Brazil, were analyzed and compared, regarding their
Lucineide Gonçalves, Roberto Magalhães Pinto, J Júlio Vicente, Dely Noronha, Delir Corrêa Gomes   +4 more
doaj   +1 more source

Genetic analysis of cholesterol accumulation in inbred mice

Journal of Lipid Research, 2001
Genetic linkage analysis in the laboratory mouse identified chromosomal regions containing genes that contribute to cholesterol accumulation in the liver and plasma.
Margrit Schwarz, Daphne L. Davis, Bertrand R. Vick, David W. Russell   +3 more
doaj   +1 more source

Gender associated effects of the ethanolic extracts of Chinese propolis on the hepatic transcriptome in ethanol-treated mice [PDF]

Iranian Journal of Basic Medical Sciences, 2019
Objective(s): The current study investigated the potential hepatoprotective effects of the ethanolic extracts of Chinese propolis (EECP) on ethanol-induced fatty liver in mice.Materials and Methods: C57BL/6J mice were orally gavaged with 50% ethanol ...
Manhong Ye, Mengting XU, Mengmeng Ding, Chao Ji, Jian Ji, Fubiao Ji, Wanhong Wei, Shengmei Yang, Bin Zhou   +8 more
doaj   +1 more source

A schematic representation of tularemia pathogenesis in vaccinated inbred C57Bl/6 versus outbred SW Mice.

, 2018
Vaccinated outbred SW and inbred C57BL/6 mice handle the progression and outcome of tularemia disease in different ways. Vaccinated SW mice in comparison to C57BL/6 mice engage early Th1 and Th17 cytokines, along with controlled production of pro ...
Edmund J. Gosselin (212969), Sudeep Kumar (205149), Sarah J. Rosa (6069251), Raju Sunagar (727875), Prachi Namjoshi (5879546), Karsten R. O. Hazlett (212973)   +5 more
core   +1 more source

Increased Disarray of Extracellular Matrix Collagen‐I Fiber Network and Compromised Biomechanics in Aortae From Marfan‐Syndrome Mice Assessed Through Combined Opto‐Biomechatronics

Advanced Science, EarlyView.
Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Dominik Schneidereit, Anika Nagel, Vanessa I. T. Zwaans, Laureen Schurr, Jonas Ahr, Michael Haug, Anna Piluso, Alexandra Sporkova, Matthias Karck, Andreas H. Wagner, Oliver Friedrich   +10 more
wiley   +1 more source