Results 61 to 70 of about 1,442,388 (221)

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

open access: yesCytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith   +9 more
wiley   +1 more source

Genetic variation in testicular development in mice of the C57BL/10ScSn, C57BL/6By and BALB/cBy strains and the CXB recombinant-inbred lines [PDF]

open access: yesReproduction, 1989
Summary. When compared with C57BL/6By mice, BALB/cBy mice had testes that were 41% heavier at 60 days of age and seminiferous tubules that were 41% greater in cross-sectional area at 120 days. Absolute testicular weight did not increase between 60 and 120 days of age in either C57BL/6By or C57BL/10ScSn mice but did in BALB mice, paralleling changes in ...
N M, Shukri, J G, Shire
openaire   +2 more sources

A Reversible Clearing Strategy Enables Robust Label‐Free Phase Imaging of Thick Tissues

open access: yesLaser &Photonics Reviews, EarlyView.
The principle of a reversible clearing strategy via glycerol and tartrazine solution (GTS) for robust whole‐slide label‐free phase imaging of thick tissue slices via high‐throughput Fourier ptychographic microscopy (FPM) and lensless digital holographic microscopy (LDHM). ABSTRACT Thick biological specimens impose strong scattering and attenuation that
Mikołaj Krysa   +5 more
wiley   +1 more source

Immune responses of different mouse strains after challenge with equivalent lethal doses of toxoplasma Gondii

open access: yesParasite, 2004
Most immunological studies that utilize different strains of inbred mice following T. gondii infection fail to compensate for differences in host susceptibility to the size of the parasite innoculum.
Lee Y.H., Kasper L.H.
doaj   +1 more source

Geometric morphometrics defines shape differences in the cortical area map of C57BL/6J and DBA/2J inbred mice

open access: yesBMC Neuroscience, 2006
Background We previously described planar areal differences in adult mouse visual, somatosensory, and neocortex that collectively discriminated C57BL/6J and DBA/2J inbred strain identity.
Guan Monica   +3 more
doaj   +1 more source

Immunological and nonimmunological control of severity of Trypanosoma musculi infections in C3H and C57BL/6 inbred mice [PDF]

open access: yesInfection and Immunity, 1989
Studies concerned with the mechanisms responsible for relative resistance or susceptibility of strains of inbred mice to Trypanosoma musculi infections are presented. Treatment with 400 rads of ionizing radiation, silica dust, or trypan blue (reticuloendothelial blocking agents) rendered C3H mice unable to control the initial maximum level of parasite ...
J W, Albright, J F, Albright
openaire   +2 more sources

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

open access: yesPhytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li   +14 more
wiley   +1 more source

Strain-specific differences in cerulein-induced acute and recurrent acute murine pancreatitis

open access: yesScientific Reports
Hyperstimulation with the secretagogue cerulein is a commonly used experimental model to study acute, recurrent acute and chronic pancreatitis in mice.
Alexandra Demcsák   +3 more
doaj   +1 more source

Shortcoming of the Mouse Model of Postoperative Ileus: Small Intestinal Lengths Have Similar Variations in In- and Outbred Mice and Cannot Be Predicted by Allometric Parameters

open access: yesBiomedicines
Background/Objectives: The mouse model of postoperative ileus separates the gastrointestinal tract into 15 sections, 10 of which are in the small intestine, to measure intestinal transit time.
Maximiliane von Stumberg   +3 more
doaj   +1 more source

Quantitative analysis of mouse urine volatiles: in search of MHC-dependent differences. [PDF]

open access: yesPLoS ONE, 2007
Genes of the major histocompatibility complex (MHC), which play a critical role in immune recognition, influence mating preference and other social behaviors in mice.
Frank Röck   +3 more
doaj   +1 more source

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