Results 61 to 70 of about 1,340,693 (219)

Immunological and nonimmunological control of severity of Trypanosoma musculi infections in C3H and C57BL/6 inbred mice [PDF]

Infection and Immunity, 1989
Studies concerned with the mechanisms responsible for relative resistance or susceptibility of strains of inbred mice to Trypanosoma musculi infections are presented. Treatment with 400 rads of ionizing radiation, silica dust, or trypan blue (reticuloendothelial blocking agents) rendered C3H mice unable to control the initial maximum level of parasite ...
J W, Albright, J F, Albright
openaire   +2 more sources

A Reversible Clearing Strategy Enables Robust Label‐Free Phase Imaging of Thick Tissues

Laser &Photonics Reviews, EarlyView.
The principle of a reversible clearing strategy via glycerol and tartrazine solution (GTS) for robust whole‐slide label‐free phase imaging of thick tissue slices via high‐throughput Fourier ptychographic microscopy (FPM) and lensless digital holographic microscopy (LDHM). ABSTRACT Thick biological specimens impose strong scattering and attenuation that
Mikołaj Krysa, Anna Chwastowicz, Małgorzata Lenarcik, Paweł Matryba, Piotr Zdańkowski, Maciej Trusiak   +5 more
wiley   +1 more source

The role of the small intestine in the development of dietary fat-induced obesity and insulin resistance in C57BL/6J mice [PDF]

, 2008
Background Obesity and insulin resistance are two major risk factors underlying the metabolic syndrome. The development of these metabolic disorders is frequently studied, but mainly in liver, skeletal muscle, and adipose tissue.
Mechteld M Grootte Bromhaar, Jansen, Jenny, de Groot Philip J, de Groot, P.J., Hooiveld Guido JEJ, Jansen Jenny, Vermeulen, J.J., Nicole JW de Wit, Jansen, J., Müller, M.R., Bosch-Vermeulen, Hanneke, van der Meer, Roelof, de Wit, Nicole J. W., Meer, R., van der, Bromhaar Mechteld, Wit, N.J.W., de, Philip J de Groot, Bosch-Vermeulen Hanneke, Hooiveld, Guido J. E. J., Müller Michael, Müller, Michael, Grootte Bromhaar, M.M., Michael Müller, de Groot, Philip J., Hanneke Bosch-Vermeulen, de Wit Nicole JW, Roelof van der Meer, de Wit, N.J.W., Bromhaar, Mechteld M. Grootte, van der Meer, R., Jenny Jansen, Groot, P.J., de, Guido JEJ Hooiveld, Hooiveld, G.J.E.J., van der Meer Roelof   +34 more
core   +2 more sources

Development of a Model of the Acute and Delayed Effects of High Dose Radiation Exposure in Jackson Diversity Outbred Mice; Comparison to Inbred C57BL/6 Mice [PDF]

, 2020
Development of medical countermeasures against radiation relies on robust animal models for efficacy testing. Mouse models have advantages over larger species due to economics, ease of conducting aging studies, existence of historical databases, and ...
Barry P. Katz, Miller, Steve J., Sampson, Carol H., Feng, Hailin, Hailin Feng, Unthank, Joseph L., Steven J. Miller, Alexa Fisher, Hui Lin Chua, Patterson, Andrea M., Katz, Barry P., Andrea M. Patterson, Carol H. Sampson, Fisher, Alexa, MacVittie, Thomas J., Plett, P. Artur, Orschell, Christie M., P. Artur Plett, Joseph L. Unthank, Christie M. Orschell, Thomas J. MacVittie, Chua, Hui Lin   +21 more
core   +1 more source

Strain-specific differences in cerulein-induced acute and recurrent acute murine pancreatitis

Scientific Reports
Hyperstimulation with the secretagogue cerulein is a commonly used experimental model to study acute, recurrent acute and chronic pancreatitis in mice.
Alexandra Demcsák, Thanh Tran, Miklós Sahin-Tóth, Andrea Geisz-Fremy   +3 more
doaj   +1 more source

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

Brain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen, Zhengjun Wang, Jiaxing Wang, Dehui Kong, Xusheng Wang, Lu Lu, Peter T. Nelson, Fu‐Ming Zhou, Francesca‐Fang Liao   +8 more
wiley   +1 more source

Genetic polymorphisms among C57BL/6 mouse inbred strains [PDF]

, 2014
Mice from the inbred C57BL/6 strain have been commonly used for the generation and analysis of transgenic and knockout animal models. However, several C57BL/6 substrains exist, and these are genetically and phenotypically different.
Landel, C. P., Montoliu, Lluís, Chagoyen, Mónica, Alonso, Rosario, González-Neira, A., López-Moreno, J. A., López-Jiménez, A., Cantero, Marta, Benítez, Javier, Pazos, Florencio, Zurita, Esther   +10 more
core   +1 more source

Systematic Comparison of High‐Fat Diet– and Streptozotocin‐Induced Prediabetic Obese C57BL/6J Mouse Models: A Sex‐Based Protocol Optimization Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Animal models of prediabetes (Pre‐DM) are essential for studying metabolic disease and testing therapies, yet high‐fat diet (HFD) and HFD‐plus‐streptozotocin (STZ) protocols vary in feeding duration, STZ dose, and diagnostic criteria and rarely account for sex.
Min Xu, Chao Ke, Yangkun Liu, Wenying Shi, Yang Cao, Zhengyu Li, Yi Xiao, Wei Zhang   +7 more
wiley   +1 more source

A Combined Adjuvant TF–Al Consisting of TFPR1 and Aluminum Hydroxide Augments Strong Humoral and Cellular Immune Responses in Both C57BL/6 and BALB/c Mice

Vaccines, 2021
TFPR1 is a novel adjuvant for protein and peptide antigens, which has been demonstrated in BALB/c mice in our previous studies; however, its adjuvanticity in mice with different genetic backgrounds remains unknown, and its adjuvanticity needs to be ...
Qiao Li, Zhihua Liu, Yi Liu, Chen Liang, Jiayi Shu, Xia Jin, Chuanyou Li, Zhihua Kou   +7 more
doaj   +1 more source

Distinct EEG Features and Sleep/Wake Behaviour Predict Anxiety Phenotypes in Mice

Journal of Sleep Research, EarlyView.
ABSTRACT Preoperative anxiety is a prevalent clinical problem linked to adverse surgical outcomes, including elevated pain, prolonged hospital stays and increased risk of postoperative delirium. Current assessments rely heavily on subjective measures, necessitating objective biomarkers.
A. Altunkaya, K. M. Mengel, M. V. Schmidt, B. Solak, M. Kreuzer, G. Rammes, G. Schneider, T. Fenzl   +7 more
wiley   +1 more source