Results 61 to 70 of about 225,250 (196)

Superovulation using the combined administration of inhibin antiserum and equine chorionic gonadotropin increases the number of ovulated oocytes in C57BL/6 female mice. [PDF]

open access: yesPLoS ONE, 2015
Superovulation is a reproductive technique generally used to produce genetically engineered mice. Superovulation in mice involves the administration of equine chorionic gonadotropin (eCG) to promote follicle growth and then that of human chorionic ...
Toru Takeo, Naomi Nakagata
doaj   +1 more source

Predominant contribution of cis-regulatory divergence in the evolution of mouse alternative splicing [PDF]

open access: yes, 2015
Divergence of alternative splicing represents one of the major driving forces to shape phenotypic diversity during evolution. However, the extent to which these divergences could be explained by the evolving cis-regulatory versus trans-acting factors ...
Ballegeer, Marlies   +4 more
core   +2 more sources

The sensitivity of murine spermiogenesis to miglustat is a quantitative trait: a pharmacogenetic study

open access: yesReproductive Biology and Endocrinology, 2007
Background A major event in the post-meiotic development of male germ cells is the formation of the acrosome. This process can be perturbed in C57BL/6 mice by administration of the small molecule miglustat (N-butyldeoxynojirimycin, NB-DNJ). The miglustat-
Boomkamp Stephanie   +8 more
doaj   +1 more source

Radiation-induced myeloid leukemia in murine models. [PDF]

open access: yes, 2014
The use of radiation therapy is a cornerstone of modern cancer treatment. The number of patients that undergo radiation as a part of their therapy regimen is only increasing every year, but this does not come without cost.
Davoren, Michael   +2 more
core   +2 more sources

Experimental Infection of Inbred Mice with Herpes Simplex Virus. III. Comparison between Newborn and Adult C57BL/6 Mice

open access: yesJournal of General Virology, 1982
We have previously shown that adult C57BL/6 mice are relatively resistant to intraperitoneal (i.p.) infection with herpes simplex virus type 1 (HSV-1). Here we show that newborn mice of the strain C57BL/6 are highly susceptible to i.p. infection with HSV-1. Newborn C57BL/6 mice, in contrast to adult mice, did not develop natural killer cell activity in
R, Zawatzky, H, Engler, H, Kirchner
openaire   +2 more sources

Interfrontal Bone Among Inbred Strains of Mice and QTL Mapping

open access: yesFrontiers in Genetics, 2019
The interfrontal bone (IF) is a minor skeletal trait residing between the frontal bones. IF is considered a quasi-continuous trait. Genetic and environmental factors appear to play roles in its development. The mechanism(s) underlying IF bone development
Heather Zimmerman   +4 more
doaj   +1 more source

Pdxdc1 modulates prepulse inhibition of acoustic startle in the mouse. [PDF]

open access: yes, 2017
Current antipsychotic medications used to treat schizophrenia all target the dopamine D2 receptor. Although these drugs have serious side effects and limited efficacy, no novel molecular targets for schizophrenia treatment have been successfully ...
Boutros, PC   +5 more
core   +1 more source

Emotion and cognition in high and low stress sensitive mouse strains: a combined neuroendocrine and behavioral study in BALB/c and C57BL/6J mice

open access: yesFrontiers in Behavioral Neuroscience, 2007
Emotionally arousing experiences and stress influence cognitive processes and vice versa. Understanding the relations and interactions between these three systems forms the core of this study. We tested two inbred mouse strains (BALB/c, C57BL/6J; male; 3-
Vera Brinks   +3 more
doaj   +1 more source

Detection and Mapping of Quantitative Trait Loci that Determine Responsiveness [PDF]

open access: yes, 2004
Exposure to 70% N2O evokes a robust antinociceptive effect in C57BL/6 (B6) but not in DBA/2 (D2) inbred mice. This study was conducted to identify quantitative trait loci (QTL) in the mouse genome that might determine responsiveness to N2O.
Belknap, John K.   +4 more
core   +1 more source

Genetic regulation of mouse liver metabolite levels. [PDF]

open access: yes, 2014
We profiled and analyzed 283 metabolites representing eight major classes of molecules including Lipids, Carbohydrates, Amino Acids, Peptides, Xenobiotics, Vitamins and Cofactors, Energy Metabolism, and Nucleotides in mouse liver of 104 inbred and ...
Bennett, Brian J   +11 more
core   +1 more source

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