Results 81 to 90 of about 1,340,693 (219)

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

Biological Reviews, Volume 101, Issue 5, Page 2408-2426, October 2026.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater, Adam Dušek, Aleksandra Bartelik, Silvia Mandillo, Elisabetta Golini, Mara Rigamonti, Rasneer Sonia Bains, Hamish Forrest, Marion Rivalan, Melissa Long, Anna Kiryk, Lars Lewejohann, Nuno Henrique Franco   +12 more
wiley   +1 more source

Mechanisms controlling anaemia in Trypanosoma congolense infected mice. [PDF]

, 2009
Trypanosoma congolense are extracellular protozoan parasites of the blood stream of artiodactyls and are one of the main constraints on cattle production in Africa.
de Angelis Martin Hrabé, Eckard Wolf, Naessens, Jan, Fuchs Helmut, Hulme, Helen, Kemp, Stephen, Alimohammadian, M.H., Wolf, Eckard, Morris Agaba, Noyes, Harry A., Hrabě de Angelis, M., de Angelis, Martin Hrabé, Agaba, M., Angelis, M.H. de, Mohammad H Alimohammadian, Martin Hrabé de Angelis, Brass Andy, Hulme Helen, Delnaz Rosh, Rathkolb, Birgit, Roshandel, Delnaz, Noyes Harry A., Rathkolb, B., Iraqi, Fuad, Fuchs, H., Hrabé de Angelis, Martin, Stephen Kemp, Jan Naessens, Wolf, E., Naessens Jan, Alimohammadian Mohammad H., Gailus-Durner, V., Gailus-Durner Valerie, Martin Hrabe ́ De Angelis, Kemp, S., Brass, Andy, Helmut Fuchs, Agaba Morris, Iraqi Fuad, Harry A. Noyes, Andy Brass, Noyes, H.A., Helen Hulme, Agaba, Morris, Kemp, Stephen J., Iraqi, F., Iraqi, F.A., Kemp Stephen, Brass, A., Harry A Noyes, Roshandel, D., Wolf Eckard, Rathkolb Birgit, Naessens, J., Delnaz Roshandel, Birgit Rathkolb, Brass, Andy; id_orcid, Alimohammadian, Mohammad H., Fuchs, Helmut, Fuad Iraqi, Wolf, Eckhard, Valerie Gailus-Durner, Hulme, H., Gailus-Durner, Valerie, Mohammad H. Alimohammadian, Roshandel Delnaz, Noyes, H.A. ; Alimohammadian, M.H. ; Agaba, M. ; Brass, A. ; Fuchs, H. ; Gailus-Durner, V. ; Hulme, H. ; Iraqi, F. ; Kemp, S. ; Rathkolb, B. ; Wolf, E. ; Hrabé de Angelis, M. ; Roshandel, D. ; Naessens, J.   +66 more
core   +2 more sources

Evaluating the Validity of Model Organisms: A Review and a New Framework for Biologists

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
This article provides an overview on model organisms and proposes a new framework for assessing the extent to which it is justified to generalize the results obtained from a given organism. It covers both studies of human diseases and those focused on general biological processes. The first part of the article is a review on model organisms.
Héloïse Athéa, Nicolas Heck
wiley   +1 more source

Placentophagia in Nonpregnant Nulliparous Mice: A Genetic Investigation [PDF]

, 1975
The genetic influence on the response of nonpregnant nulliparous mice to foster placenta was investigated. Two highly inbred strains (BALB/cBy and C57BL/6By), their F1 hybrids, a backcross generation, and seven recombinant-inbred strains derived from the
Kristal, M B, Kristal, Dr. Mark B., Eleftheriou, Basil E., Eleftheriou, B E   +3 more
core  

The effects of levetiracetam and a new 4-phenylpyrrolidone derivative GIZh-290 in a closed cross-maze in BALB/c and C57BL / 6 mice

Фармакокинетика и Фармакодинамика, 2017
The study was aimed to compare the psychopharmacological effects of 2 anticonvulsant drugs levetiracetam ((S)-2-(2-oxopyrrolidin-1-yl) butanamide) and the new compound, GIZh-290 (2-oxo-4-phenylpyrrolidine-1-yl) acetic acid) on behavioral spectra of ...
I. G. Kovalev, E. V. Vasileva, R. O. Bokov, R. M. Salimov, G. I. Kovalev   +4 more
doaj  

The hypervirulent Type-1/Type-17 phenotype of Cryptococcus neoformans clinical isolates is specific to A/J mice

Infection and Immunity
Cryptococcus neoformans is a fungal pathogen that causes cryptococcal meningitis in immunocompromised individuals. Both host- and pathogen-specific factors are known to affect patient outcome, and recent studies showed that strain-specific differences in
Minna Ding, Katrina M. Jackson, Madeline Harris-Gordon, Thamotharampillai Dileepan, David B. Meya, Kirsten Nielsen   +5 more
doaj   +1 more source

Behavioral profiles of three C57BL/6 substrains

Frontiers in Behavioral Neuroscience, 2010
C57BL/6 inbred strains of mice are widely used in knockout and transgenic research. To evaluate the loss-of-function and gain-of-function effects of the gene of interest, animal behaviors are often examined.
Naoki Matsuo, Naoki Matsuo, Keizo Takao, Keizo Takao, Keizo Takao, Keizo Takao, Kazuo Nakanishi, Nobuyuki Yamasaki, Nobuyuki Yamasaki, Koichi Tanda, Koichi Tanda, Tsuyoshi Miyakawa, Tsuyoshi Miyakawa, Tsuyoshi Miyakawa, Tsuyoshi Miyakawa, Tsuyoshi Miyakawa   +15 more
doaj   +1 more source

NONcNZO10/LtJ and TALLY‐HO/JngJ Mice as Novel Models of Diabetic Peripheral Neuropathy

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Animal models of diabetic peripheral neuropathy (DPN) are essential for understanding disease mechanisms and evaluating therapies. We characterized two polygenic mouse strains, RCS10 and TH, and found that both developed obesity, hyperglycemia, dyslipidemia, and DPN.
Stéphanie A. Eid, Andrew D. Carter, Emily J. Koubek, John M. Hayes, Diana M. Rigan, Chloe Kiriluk, Crystal M. Pacut, Phillipe D. O'Brien, Jihyun Park, Dae‐Gyu Jang, Eva L. Feldman   +10 more
wiley   +1 more source

Sensory Contact Model: Protocol, Control, Applications [PDF]

, 2009
Among the models that become more and more popular in behavioral neuroscience are biosocial models, which allow studying the consequences of chronic social conflicts and social stress in animals. The sensory contact model appears to represent one of such
N.N. Kudryavtseva
core  

Metabolic Shifts Precede Cognitive Decline in the Male hAß‐KI Alzheimer's Mouse Model

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
A major barrier in Alzheimer's disease (AD) research is the lack of animals that recapitulate sporadic AD. The humanized amyloid‐beta knock‐in mice (hAß‐KI) exhibit age‐dependent cognitive decline and beta‐amyloid accumulation. However, limited research has been conducted related to AD risk factors and sex‐specific responses.
Evelin Melekh, Emma L. Cook, Julia G. Stante, Amélie A. T. Marais, Ahmad Mohammad, Shawn M. Beaudette, Wendy E. Ward, Val A. Fajardo, Rebecca E. K. MacPherson   +8 more
wiley   +1 more source