Results 101 to 110 of about 1,340,693 (219)

Insights Into the Interplay Between the Senescent Cells and Immune Cells

Aging Cell, Volume 25, Issue 9, September 2026.
Kidney aging is associated with increased proximal tubular senescence and leukocyte infiltration. Senolytic treatment reduces senescent cell burden and overall immune cell infiltration. However, macrophages remain enriched around residual senescent cells.
Martin Jaros, Marco Schmidt, Lavinia Neubert, Jan‐Christopher Kamp, Sibylle von Vietinghoff, Jan Hinrich Bräsen, Roland Schmitt, Anette Melk   +7 more
wiley   +1 more source

Malaria-filaria coinfection in mice makes malarial disease more severe unless filarial infection achieves patency [PDF]

, 2005
Coinfections are common in natural populations, and the literature suggests that helminth coinfection readily affects how the immune system manages malaria.
Lamb, Tracey J, Andrea L. Graham, Tracey J. Lamb, Andrew F. Read, A Andrew F. Read, Judith E. Allen, Graham, Andrea L, Read, Andrew F, Allen, Judith E   +8 more
core   +2 more sources

Rethinking Senescence Hallmarks in the Brain: Lessons From Peripheral Tissues and Challenges in Defining Neuronal Senescence

Aging Cell, Volume 25, Issue 9, September 2026.
Neuronal senescence‐like states arise from convergent intrinsic and disease‐associated stressors and are linked to persistent dysfunction, SASP‐like signaling, and altered glial interactions. Because no single marker is definitive in post‐mitotic neurons, multimarker and context‐dependent frameworks are required to define their role in ...
Miraj Ud Din Momand, Kristina Macova, Dominika Fricova   +2 more
wiley   +1 more source

Effects of restraint stress on the regulation of hippocampal glutamate receptor and inflammation genes in female C57BL/6 and BALB/c mice

Neurobiology of Stress, 2019
The two strains of inbred mice, BALB/c and C57BL/6, are widely used in pre-clinical psychiatry research due to their differences in stress susceptibility.
Joshua McWhirt, Monica Sathyanesan, Dayalan Sampath, Samuel S. Newton   +3 more
doaj   +1 more source

Improvement of Mouse Spermatozoa Freezing at −80°C With Ascorbic Acid 2‐Glucoside at Thawing Phase

Andrology, Volume 14, Issue 6, Page 1647-1655, September 2026.
ABSTRACT Background Sperm cryopreservation is the most common method to maintain a great number of mutant mouse lines. However, the use of liquid nitrogen (LN2) for freezing presents considerable problems in terms of cost, safety, and accessibility. For this reason, the storage of semen samples at ‐80° in ultra‐freezers has been increasingly used in ...
Alessia Paradiso, Renata Paoletti, Simone Cassetti, Nicola Bernabò, Barbara Barboni, Marcello Raspa, Ferdinando Scavizzi   +6 more
wiley   +1 more source

Induction of lipid oxidation by polyunsaturated fatty acids of marine origin in small intestine of mice fed a high-fat diet [PDF]

, 2009
Background. Dietary polyunsaturated fatty acids (PUFA), in particular the long chain marine fatty acids docosahexaenoic (DHA) and eicosapentaenoic (EPA), are linked to many health benefits in humans and in animal models.
Schothorst, E.M., van, Evert M van Schothorst, Annelies Bunschoten, Jaap Keijer, van Schothorst, E.M., Molthoff, J.W., Keijer, J., Flachs, P., Bunschoten, A., Kopecky, J., Vink, C., Franssen-Hal, N.L.W., van, van Franssen-Hal, N.L.W., Ondrej Kuda, Carolien Vink, Nicole LW Franssen-van Hal, Guido JEJ Hooiveld, Pavel Flachs, Kuda, O., Hooiveld, G.J.E.J., Jan Kopecky, Jos Molthoff   +21 more
core   +1 more source

Early hippocampal high-amplitude rhythmic spikes predict post-traumatic epilepsy in mice

Frontiers in Neuroscience
Oscillations, a highly conserved brain function across mammalian species, play a pivotal role in both brain physiology and pathology. Traumatic brain injury (TBI) frequently results in subacute and chronic alterations in brain oscillations, which are ...
Tyler Shannon, Noah Levine, Rina Dirickson, Yuyan Shen, Christopher Cotter, Christopher Cotter, Noora Rajjoub, Julie Fitzgerald, Julie Fitzgerald, Fernando Pardo-Manuel de Villena, Fernando Pardo-Manuel de Villena, Olga Kokiko-Cochran, Olga Kokiko-Cochran, Olga Kokiko-Cochran, Bin Gu, Bin Gu   +15 more
doaj   +1 more source

Differences in the Flexibility of Switching Learning Strategies and CREB Phosphorylation Levels in Prefrontal Cortex, Dorsal Striatum, and Hippocampus in Two Inbred Strains of Mice

Frontiers in Behavioral Neuroscience, 2016
Flexibility in using different learning strategies was assessed in two different inbred strains of mice, the C57BL/6 and DBA/2 strains. Mice were trained sequentially in two different Morris water maze protocols that tested their ability to switch their ...
Woo-Hyun Cho, Jung-Soo Han
doaj   +1 more source

Haploinsufficiency of the Tyrosine Hydroxylase Gene in the Inbred C57BL/6J Strain Alters Behavior, Immunity, and Oxidative Stress, Especially After Acute Stress

Catecholamines (CA) are considered to play key roles in acute stress responses, but they also regulate important functions of the nervous, immune, and endocrine systems and are essential for body homeostasis and health.
Fuente Del Rey, María Mónica De La, De la Fuente, M\uf3nica, Mónica De la Fuente, Garrido, Antonio, F\ue9lix, Judith, Antonio Garrido, Judith Félix, Félix Escalera, Judith   +7 more
core   +1 more source

Diet1, bile acid diarrhea, and FGF15/19: mouse model and human genetic variants[S]

Journal of Lipid Research, 2018
Diet1 modulates intestinal production of the hormone, fibroblast growth factor (FGF)15, which signals in liver to regulate bile acid synthesis. C57BL/6ByJ mice with a spontaneous Diet1-null mutation are resistant to hypercholesterolemia compared with ...
Jessica M. Lee, Jessica R. Ong, Laurent Vergnes, Thomas Q. de Aguiar Vallim, Jonathan Nolan, Rita M. Cantor, JulianR.F. Walters, Karen Reue   +7 more
doaj   +1 more source