Results 1 to 10 of about 1,429,370 (225)

Into the Wild: A novel wild-derived inbred strain resource expands the genomic and phenotypic diversity of laboratory mouse models. [PDF]

open access: yesPLoS Genetics
The laboratory mouse has served as the premier animal model system for both basic and preclinical investigations for over a century. However, laboratory mice capture only a subset of the genetic variation found in wild mouse populations, ultimately ...
Beth L Dumont   +14 more
doaj   +4 more sources

Inbred Strain Variant Database (ISVdb): A Repository for Probabilistically Informed Sequence Differences Among the Collaborative Cross Strains and Their Founders [PDF]

open access: yesG3: Genes, Genomes, Genetics, 2017
The Collaborative Cross (CC) is a panel of recently established multiparental recombinant inbred mouse strains. For the CC, as for any multiparental population (MPP), effective experimental design and analysis benefit from detailed knowledge of the ...
Daniel Oreper   +4 more
doaj   +2 more sources

Establishment of a zebrafish inbred strain, M-AB, capable of regular breeding and genetic manipulation [PDF]

open access: yesScientific Reports
Inbred strains of organisms are genetically highly uniform and thus useful for life science research. We have previously reported the ongoing generation of the zebrafish IM strain from the India (IND) strain through full sib-pair mating for 16 ...
Kenichiro Sadamitsu   +9 more
doaj   +2 more sources

Inbred mouse strains and genetic stability: a review

open access: yesAnimal, 2011
Inbred mice were essential animal models for scientific research during the 20th century and will contribute decisive results in the current and next centuries.
J. Casellas
doaj   +3 more sources

Inbred strains of Xenopus tropicalis show morphological and genetic variation [PDF]

open access: yesScientific Reports
The emergence of individuality and morphological divergence within a population is crucial for evolutionary potential. This study investigated genetic and phenotypic variation among four inbred strains of Xenopus tropicalis, a promising model amphibian ...
Takeshi Igawa   +6 more
doaj   +2 more sources

Morphometric Characteristic of Black Soldier Fly (Hermetia illucens) · Wuhan Strain and Its Egg Production Improved by Selectively Inbreeding

open access: yesLife, 2022
The use of black soldier fly (BSF) larvae to recycle various organic materials while producing biomass for use as feed is well established. Variety selection is important from the perspective of application.
Minmin Cai   +10 more
doaj   +1 more source

The new attenuated strain of Mycobacterium tuberculosis BN. Characteristics and vaccine properties

open access: yesТуберкулез и болезни лёгких, 2021
The objective of the study: to obtain a live attenuated strain and investigate its properties by multiple cultures of the virulent strain of Mycobacterium tuberculosis H37Rv.Subjects and Methods.
B. V. Nikonenko   +5 more
doaj   +1 more source

A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior. [PDF]

open access: yesPLoS ONE, 2009
Glyoxalase 1 (Glo1) has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. We used mouse Affymetrix exon arrays to detect copy number variants (CNV) among inbred mouse strains and thereby identified a ...
Richard Williams   +13 more
doaj   +1 more source

Use of C57BL/6N mice on the variety of immunological researches

open access: yesLaboratory Animal Research, 2017
Inbred mice are an essential animal strain for research as they can improve the reproducibility and reliability of study results. The establishment of new inbred lines is continuing, and new inbred lines are being used in many research fields. C57BL/6 is
Hyun Keun Song, Dae Youn Hwang
doaj   +1 more source

The UCSF Mouse Inventory Database Application, an Open Source Web App for Sharing Mutant Mice Within a Research Community

open access: yesG3: Genes, Genomes, Genetics, 2020
The UCSF Mouse Inventory Database Application is an open-source Web App that provides information about the mutant alleles, transgenes, and inbred strains maintained by investigators at the university and facilitates sharing of these resources within the
Estelle Wall   +7 more
doaj   +1 more source

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