Results 71 to 80 of about 225,250 (196)

Behavioral profiles of three C57BL/6 substrains

Frontiers in Behavioral Neuroscience, 2010
C57BL/6 inbred strains of mice are widely used in knockout and transgenic research. To evaluate the loss-of-function and gain-of-function effects of the gene of interest, animal behaviors are often examined.
Naoki Matsuo, Naoki Matsuo, Keizo Takao, Keizo Takao, Keizo Takao, Keizo Takao, Kazuo Nakanishi, Nobuyuki Yamasaki, Nobuyuki Yamasaki, Koichi Tanda, Koichi Tanda, Tsuyoshi Miyakawa, Tsuyoshi Miyakawa, Tsuyoshi Miyakawa, Tsuyoshi Miyakawa, Tsuyoshi Miyakawa   +15 more
doaj   +1 more source

Identifying reliable traits across laboratory mouse exploration arenas: A meta-analysis [PDF]

, 2012
This study is a meta-analysis of 367 mice from a collection of behaviour neuroscience and behaviour genetic studies run in the same lab in Zurich, Switzerland.
Hans-Peter Lipp, Michael J. Galsworthy, Rime Madani   +2 more
core   +2 more sources

Genetic Dissection of a QTL Affecting Bone Geometry. [PDF]

, 2017
Parameters of bone geometry such as width, length, and cross-sectional area are major determinants of bone strength. Although these traits are highly heritable, few genes influencing bone geometry have been identified.
Farber, Charles R, Medrano, Juan F, Sabik, Olivia L   +2 more
core   +2 more sources

The effects of levetiracetam and a new 4-phenylpyrrolidone derivative GIZh-290 in a closed cross-maze in BALB/c and C57BL / 6 mice

Фармакокинетика и Фармакодинамика, 2017
The study was aimed to compare the psychopharmacological effects of 2 anticonvulsant drugs levetiracetam ((S)-2-(2-oxopyrrolidin-1-yl) butanamide) and the new compound, GIZh-290 (2-oxo-4-phenylpyrrolidine-1-yl) acetic acid) on behavioral spectra of ...
I. G. Kovalev, E. V. Vasileva, R. O. Bokov, R. M. Salimov, G. I. Kovalev   +4 more
doaj  

The hypervirulent Type-1/Type-17 phenotype of Cryptococcus neoformans clinical isolates is specific to A/J mice

Infection and Immunity
Cryptococcus neoformans is a fungal pathogen that causes cryptococcal meningitis in immunocompromised individuals. Both host- and pathogen-specific factors are known to affect patient outcome, and recent studies showed that strain-specific differences in
Minna Ding, Katrina M. Jackson, Madeline Harris-Gordon, Thamotharampillai Dileepan, David B. Meya, Kirsten Nielsen   +5 more
doaj   +1 more source

Effect of dietary cholesterol and taurocholate on cholesterol 7 alpha-hydroxylase and hepatic LDL receptors in inbred mice

Journal of Lipid Research, 1993
Compared to BALB/c mice, inbred C57BL/6 mice are more susceptible to developing fatty streak atherosclerotic lesions when fed a cholesterol-rich diet containing taurocholate. We examined the metabolic basis for the taurocholate requirement.
S Dueland, J Drisko, L Graf, D Machleder, AJ Lusis, RA Davis   +5 more
doaj   +1 more source

In utero ultrafine particulate matter exposure causes offspring pulmonary immunosuppression. [PDF]

, 2019
Early life exposure to fine particulate matter (PM) in air is associated with infant respiratory disease and childhood asthma, but limited epidemiological data exist concerning the impacts of ultrafine particles (UFPs) on the etiology of childhood ...
Chang, Richard C-A, Golding, Michael C, Johnson, Natalie M, Langley, Rebecca, Lau, Carmen, Leal, Jeann, Li, Yixin, Molina, Mario J, Myatt, Louise G, Pulczinski, Jairus, Raju, Muppala, Rodrigues-Hoffmann, Aline, Rychlik, Kristal A, Secrest, Jeremiah R, Zamora, Misti L, Zhang, Renyi   +15 more
core  

Involvement of Mhc Loci in immune responses that are not Ir-gene-controlled [PDF]

, 1982
Twenty-nine randomly chosen, soluble antigens, many of them highly complex, were used to immunize mice of two strains, C3H and B10.RIII. Lymphnode cells from the immunized mice were restimulated in vitro with the priming antigens and the proliferative ...
C. J. Kreo, C. N. Baxevanis, C. N. Baxevanis, D. L. Longo, E. A. Lerner, E. M. Shevach, G. Corradin, H. Lemke, H. O. McDevitt, H. O. McDevitt, J. Sprent, J. T. Nepom, Jan Klein, K. Ozato, L.P. Ryder, M. Shigeta, Matko Marušić, N. Ishii, P. C. Dubriel, P. P. Jones, R. H. Schwartz, R. M. Zinkernagel, U. K. Laemmli, U. Koszinowski, Ulrich Koszinowski, V. T. Oi, Y. Hosaka, Z. A. Nagy, Zoltan A. Nagy   +28 more
core   +1 more source

Assignment of the Human and Mouse Prion Protein Genes to Homologous Chromosomes [PDF]

, 1986
Purified preparations of scrapie prions contain one major macromolecule, designated prion protein (PrP). Genes encoding PrP are found in normal animals and humans but not within the infectious particles.
Blatt, Cila, Cohn, Vivian H., DeArmond, Stephen J., Fournier, R. E. K., Heinzmann, Camilla, Klisak, Ivana, Lem, Janice, Lucero, Michael, Mohandas, T., Pruisner, Stanley B., Simon, Melvin, Sparkes, Robert S., Weiner, Leslie P., Westaway, David   +13 more
core  

Functional plasticity in the type IV secretion system of Helicobacter pylori. [PDF]

, 2012
Helicobacter pylori causes clinical disease primarily in those individuals infected with a strain that carries the cytotoxin associated gene pathogenicity island (cagPAI).
Barrozo, Roberto M, Cariaga, Taryn A, Cooke, Cara L, Cover, Timothy L, Gaddy, Jennifer A, Hansen, Lori M, Johnson, Elizabeth M, Lam, Anna M, Peek, Richard M, Solnick, Jay V, Suarez, Giovanni   +10 more
core   +1 more source