Results 31 to 40 of about 1,442,388 (221)

Quantitative Trait Loci That Determine BMD in C57BL/6J and 129S1/SvImJ Inbred Mice [PDF]

Journal of Bone and Mineral Research, 2006
Abstract BMD is highly heritable; however, little is known about the genes. To identify loci controlling BMD, we conducted a QTL analysis in a (B6 × 129) F2 population of mice. We report on additional QTLs and also narrow one QTL by combining the data from multiple crosses and through haplotype analysis.
Ishimori, N, Li, R, Walsh, K A, Korstanje, R, Rollins, J A, Petkov, P, Pletcher, M T, Wiltshire, T, Donahue, L R, Rosen, C J, Beamer, W G, Churchill, G A, Paigen, B   +12 more
openaire   +3 more sources

Anxiety-related behaviour in C57BL/6?BALB/c chimeric mice. [PDF]

, 2004
In a previous study on anxiety-related behaviours of the genetically and behaviourally distant inbred mouse strains C57BL/6 and BALB/c using the Elevated plus-maze (EPM) and Open-field (OF) apparatuses, we identified a number of variables, the factorial ...
BRUNAMONTI E., MANGIA F., D'OLIMPIO, Francesca, CAROLA V., BEVILACQUA A., RENZI P.   +5 more
core   +2 more sources

EO771, the first luminal B mammary cancer cell line from C57BL/6 mice

Cancer Cell International, 2020
Background Despite decades of therapeutic trials, effective diagnosis, many drugs available and numerous studies on breast cancer, it remains the deadliest cancer in women. In order to choose the most appropriate treatment and to understand the prognosis
Augustin Le Naour, Yvonne Koffi, Mariane Diab, Delphine Le Guennec, Stéphanie Rougé, Sahar Aldekwer, Nicolas Goncalves-Mendes, Jérémie Talvas, Marie-Chantal Farges, Florence Caldefie-Chezet, Marie-Paule Vasson, Adrien Rossary   +11 more
doaj   +1 more source

Evaluation of an outbred mouse model for Francisella tularensis vaccine development and testing.

PLoS ONE, 2018
Francisella tularensis (Ft) is a biothreat agent for which there is no FDA-approved human vaccine. Currently, there are substantial efforts underway to develop both vaccines and the tools to assess these vaccines.
Raju Sunagar, Sudeep Kumar, Prachi Namjoshi, Sarah J Rosa, Karsten R O Hazlett, Edmund J Gosselin   +5 more
doaj   +1 more source

Corticotropin-releasing factor receptors couple to multiple g-proteins to activate diverse intracellular signaling pathways in mouse hippocampus: role in neuronal excitability and associative learning [PDF]

, 2003
Corticotropin-releasing factor (CRF) exerts a key neuroregulatory control on stress responses in various regions of the mammalian brain, including the hippocampus.
Nijholt, I., Thomas Blank, Spiess, Joachim, Blank, Thomas, Spiess, J., Randeva, H., Hillhouse, E., Nijholt, Ingrid, Edward W. Hillhouse, Grammatopoulos, Dimitris K., Grammatopoulos, D., Joachim Spiess, Blank, T., Randeva, Harpal S., Grammatopoulos, Dimitris, Blank, T. (Thomas), Dimitris K. Grammatopoulos, Hillhouse, Edward W., Harpal S. Randeva, Ingrid Nijholt   +19 more
core   +1 more source

Comparative study of fertilization rates of C57BL/6NKorl and C57BL/6N mice obtained from two other sources

Laboratory Animal Research, 2017
C57BL/6N is the most widely used inbred mouse strain applied in a wide variety of research areas including cancer, cardiovascular biology, developmental biology, diabetes and obesity, genetics, immunology, neurobiology, and sensorineural research.
Woo Bin Yun, Hye Ryeong Kim, Ji Eun Kim, Jun Young Choi, Mi Rim Lee, Jin Ju Park, Bo Ram Song, Young Suk Jung, Hyun Keun Song, Joon Young Cho, Kil Soo Kim, Dae Youn Hwang   +11 more
doaj   +1 more source

Responses to ethanol in C57BL/6 versus C57BL/6 × 129 hybrid mice [PDF]

, 2012
Although genetic background alters responses to ethanol, there has not yet been a methodical quantification of differences in ethanol-related behaviors between inbred and hybrid mice commonly used in gene-targeting studies. Here, we compared C57BL/6NTac ×
Zou, Mimi E, Messing, Robert O, Robert O. Messing, Mimi E. Zou, Jana P. Lim, Janak, Patricia H, Lim, Jana P, Patricia H. Janak   +7 more
core   +1 more source

Persistence of Leishmania antigen in C57Bl/6j inbred mice infected with Leishmania (Leishmania) amazonensis [PDF]

Revista da Associação Médica Brasileira, 1999
To develop an animal model for studying mucocutaneous leishmaniasis.The hind footpad of C57Bl/6j inbred mice was experimentally infected with 10(7) Leishmania (Leishmania) amazonensis promastigote and the skin was studied through light and electron transmission microscopy and immunohistochemistry (PAP) techniques.There were morphological evidences of ...
Vasconcellos, C., Kauffman, M.R., Sotto, M. N.   +2 more
openaire   +4 more sources

Genetic polymorphisms among C57BL/6 mouse inbred strains [PDF]

, 2010
Mice from the inbred C57BL/6 strain have been commonly used for the generation and analysis of transgenic and knockout animal models. However, several C57BL/6 substrains exist, and these are genetically and phenotypically different.
Landel, C. P., Montoliu, Lluís, Chagoyen, Mónica, Alonso, Rosario, González-Neira, A., López-Moreno, J. A., López-Jiménez, A., Cantero, Marta, Benítez, Javier, Pazos, Florencio, Zurita, Esther, Mónica Chagoyen, Javier Benítez, José Antonio López-Moreno, Rosario Alonso, Esther Zurita, Anna González-Neira, Alejandro López-Jiménez, Carlisle P. Landel, Lluís Montoliu, Marta Cantero, Florencio Pazos   +21 more
core   +1 more source

Delayed Clinical and Pathological Signs in Twitcher (Globoid Cell Leukodystrophy) Mice on a C57BL/6 × CAST/Ei Background

Neurobiology of Disease, 2002
Modifier genes may account for the phenotypic variability observed in the late-onset forms of globoid cell leukodystrophy (GCL) in humans. In order to begin a search for modifier genes, the effect of genetic background on the clinical and pathological ...
Sangita Biswas, Homigol Biesiada, Todd D. Williams, Steven M. LeVine   +3 more
doaj   +1 more source