Results 21 to 30 of about 1,340,693 (219)

Junctional adhesion molecule (JAM)-C deficient C57BL/6 mice develop a severe hydrocephalus [PDF]

open access: yes, 2012
The junctional adhesion molecule (JAM)-C is a widely expressed adhesion molecule regulating cell adhesion, cell polarity and inflammation. JAM-C expression and function in the central nervous system (CNS) has been poorly characterized to date.
Michel Mittelbronn   +27 more
core   +3 more sources

Dose-dependent effects of dietary fat on development of obesity in relation to intestinal differential gene expression in C57BL/6J mice [PDF]

open access: yes, 2011
Excessive intake of dietary fat is known to be a contributing factor in the development of obesity. In this study, we determined the dose-dependent effects of dietary fat on the development of this metabolic condition with a focus on changes in gene ...
Boekschoten, Mark V.   +43 more
core   +2 more sources

Quantitative Trait Loci That Determine BMD in C57BL/6J and 129S1/SvImJ Inbred Mice [PDF]

open access: yesJournal of Bone and Mineral Research, 2006
Abstract BMD is highly heritable; however, little is known about the genes. To identify loci controlling BMD, we conducted a QTL analysis in a (B6 × 129) F2 population of mice. We report on additional QTLs and also narrow one QTL by combining the data from multiple crosses and through haplotype analysis.
Ishimori, N   +12 more
openaire   +3 more sources

Neuroimaging Evidence of Major Morpho-Anatomical and Functional Abnormalities in the BTBR T+TF/J Mouse Model of Autism [PDF]

open access: yes, 2013
BTBR T+tf/J (BTBR) mice display prominent behavioural deficits analogous to the defining symptoms of autism, a feature that has prompted a widespread use of the model in preclinical autism research.
Scattoni, Maria Luisa   +28 more
core   +1 more source

EO771, the first luminal B mammary cancer cell line from C57BL/6 mice

open access: yesCancer Cell International, 2020
Background Despite decades of therapeutic trials, effective diagnosis, many drugs available and numerous studies on breast cancer, it remains the deadliest cancer in women. In order to choose the most appropriate treatment and to understand the prognosis
Augustin Le Naour   +11 more
doaj   +1 more source

Modulation of aggression in male mice: influence of group size and cage size [PDF]

open access: yes, 2001
Aggression in group-housed male mice is known to be influenced by both cage size and group size. However, the interdependency of these two parameters has not been studied yet. In this study, the level of aggression in groups of three, five, or eight male
van Loo, P.L.P.   +18 more
core   +2 more sources

Evaluation of an outbred mouse model for Francisella tularensis vaccine development and testing.

open access: yesPLoS ONE, 2018
Francisella tularensis (Ft) is a biothreat agent for which there is no FDA-approved human vaccine. Currently, there are substantial efforts underway to develop both vaccines and the tools to assess these vaccines.
Raju Sunagar   +5 more
doaj   +1 more source

Behavioral Profiles of Genetically Selected Aggressive and Nonaggressive Male Wild House Mice in Two Anxiety Tests [PDF]

open access: yes, 2000
Artificially selected aggressive (SAL) and non-aggressive (LAL) male house mice were tested in a hexagonal tunnel maze and light–dark preference (LD) box to determine if the bidirectional selection for aggressive behavior leads to a coselection for ...
Sluyter, Frans   +13 more
core   +1 more source

Comparative study of fertilization rates of C57BL/6NKorl and C57BL/6N mice obtained from two other sources

open access: yesLaboratory Animal Research, 2017
C57BL/6N is the most widely used inbred mouse strain applied in a wide variety of research areas including cancer, cardiovascular biology, developmental biology, diabetes and obesity, genetics, immunology, neurobiology, and sensorineural research.
Woo Bin Yun   +11 more
doaj   +1 more source

Persistence of Leishmania antigen in C57Bl/6j inbred mice infected with Leishmania (Leishmania) amazonensis [PDF]

open access: yesRevista da Associação Médica Brasileira, 1999
To develop an animal model for studying mucocutaneous leishmaniasis.The hind footpad of C57Bl/6j inbred mice was experimentally infected with 10(7) Leishmania (Leishmania) amazonensis promastigote and the skin was studied through light and electron transmission microscopy and immunohistochemistry (PAP) techniques.There were morphological evidences of ...
Vasconcellos, C.   +2 more
openaire   +4 more sources

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