Sex differences in glucose metabolism of streptozotocin-induced diabetes inbred mice (C57BL/6J) [PDF]
Applied Biological Chemistry, 2020 AbstractConsidering that sex differences in glucose metabolism are observed in mice, researchers unconsciously use male mice to reduce variations by an estrogen cycle in female mice. In this study, we investigated the sex differences in glucose homeostasis in streptozotocin (STZ)-induced diabetes inbred mice (C57BL/6J).
Boyoung Kim +4 more
openaire +1 more source
Variation in the cortical area map of C57BL/6J and DBA/2J inbred mice predicts strain identity
BMC Neuroscience, 2005 Background Recent discoveries suggest that arealization of the mammalian cortical sheet develops in a manner consonant with principles established for embryonic patterning of the body.
Wu Fangbai +4 more
doaj +1 more source
Agouti C57BL/6N embryonic stem cells for mouse genetic resources. [PDF]
, 2009 We report the characterization of a highly germline competent C57BL/6N mouse embryonic stem cell line, JM8. To simplify breeding schemes, the dominant agouti coat color gene was restored in JM8 cells by targeted repair of the C57BL/6 nonagouti mutation ...
Beier, David R +8 more
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Strain-dependent variations in stress coping behavior are mediated by a 5-HT/GABA interaction within the prefrontal corticolimbic system [PDF]
, 2015 Background: Serotonin and γ- Aminobutyric acid (GABA) transmission is crucial in coping strategies. Methods: Here, using mice from 2 inbred strains widely exploited in behavioral neurochemistry, we investigated whether serotonin transmission in medial ...
ANDOLINA, DIEGO +3 more
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Placentophagia in Nonpregnant Nulliparous Mice: A Genetic Investigation [PDF]
, 1975 The genetic influence on the response of nonpregnant nulliparous mice to foster placenta was investigated. Two highly inbred strains (BALB/cBy and C57BL/6By), their F1 hybrids, a backcross generation, and seven recombinant-inbred strains derived from the
Eleftheriou, Basil E. +1 more
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A phenotypic and molecular characterization of the fmr1-tm1Cgr Fragile X mouse [PDF]
, 2004 Fragile X Syndrome is the most common form of\ud inherited mental retardation. It is also known for having\ud a substantial behavioral morbidity, including autistic features. In humans, Fragile X Syndrome is almost always\ud caused by inactivation of the
Bauchwitz, Dr. Robert P.
core +1 more source
Evaluation of an outbred mouse model for Francisella tularensis vaccine development and testing.
PLoS ONE, 2018 Francisella tularensis (Ft) is a biothreat agent for which there is no FDA-approved human vaccine. Currently, there are substantial efforts underway to develop both vaccines and the tools to assess these vaccines.
Raju Sunagar +5 more
doaj +1 more source
The effects of strain, reproductive condition, and strain of placenta donor on placentophagia in nonpregnant mice [PDF]
, 1973 The effects on placentophagia of strain, reproductive condition, and strain of placenta donor were observed in nonpregnant mice. Mice of the C57BL/6By and BALB/cBy strains were exposed to placentas of either strain after either no previous parturitional ...
Kristal, Dr. Mark B. +1 more
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Laboratory Animal Research, 2017 C57BL/6N is the most widely used inbred mouse strain applied in a wide variety of research areas including cancer, cardiovascular biology, developmental biology, diabetes and obesity, genetics, immunology, neurobiology, and sensorineural research.
Woo Bin Yun +11 more
doaj +1 more source
EO771, the first luminal B mammary cancer cell line from C57BL/6 mice
Cancer Cell International, 2020 Background Despite decades of therapeutic trials, effective diagnosis, many drugs available and numerous studies on breast cancer, it remains the deadliest cancer in women. In order to choose the most appropriate treatment and to understand the prognosis
Augustin Le Naour +11 more
doaj +1 more source