Results 41 to 50 of about 91,571 (261)

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

Advanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn, Gyu Tae Park, Dongjun Lee, Sik Yoon, Sae‐Ock Oh, Jae Ho Kim, Byoung Soo Kim   +6 more
wiley   +1 more source

Assessment of Tumor Vascularization: Immunohistochemical and Non-Invasive Methods

The International Journal of Biological Markers, 1999
Growth of solid tumors beyond a certain mass is dependent on the vascular bed from pre-existing host vasculature. The process of angiogenesis is essential not only for primary tumor growth but also for metastasis.
M. Fanelli, N. Locopo, D. Gattuso, G. Gasparini   +3 more
doaj   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Cells involved in extracellular matrix remodeling after acute myocardial infarction

Einstein (São Paulo)
Objective Evaluate the effects of VEGF165 gene transfer in the process of remodeling of the extracellular matrix after an acute myocardial infarct. Methods Wistar rats were submitted to myocardial infarction, after the ligation of the left descending ...
Larissa Ferraz Garcia, Fábio D’Aguiar Mataveli, Ana Maria Amaral Antônio Mader, Thérèse Rachell Theodoro, Giselle Zenker Justo, Maria Aparecida da Silva Pinhal   +5 more
doaj   +1 more source

Formação in vitro de túbulos capilares a partir de células de sangue de cordão umbilical humano com perspectivas para aplicação terapêutica In vitro formation of capillary tubules from human umbilical cord blood cells with perspectives for therapeutic application

Brazilian Journal of Cardiovascular Surgery, 2008
OBJETIVO: As células progenitoras endoteliais (CPE), caracterizadas pelo marcador CD133+, contribuem para a neovascularização, e o aumento no número dessas células pode ser uma ferramenta terapêutica promissora. O sangue de cordão umbilical humano contém
Alexandra Cristina Senegaglia, Paulo Roberto Slud Brofman, Carlos Alberto Mayora Aita, Bruno Dallagiovanna, Carmen Lúcia Kuniyoshi Rebelatto, Paula Hansen, Fabiane Barchiki, Marco Aurélio Krieger   +7 more
doaj   +1 more source

Nuclear Pore Mechanotransduction in Oncology: A Structural Axis of Vulnerability for Targeted Intervention

Advanced Materials, EarlyView.
Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello, Caren Rigon Mizdal, Aline Franzen da Silva, Yun Qian, Wei‐En Yuan, Victor Shahin   +5 more
wiley   +1 more source

Photodynamic effects on choroidal neovascularization and physiological choroid.

Investigative ophthalmology & visual science, 2002
To evaluate the effect of photodynamic therapy (PDT) on perfusion and vascular integrity of choroidal neovascularization (CNV) and collateral physiological choroid.In a prospective clinical trial, patients with subfoveal CNV were treated with PDT and verteporfin.
Ursula, Schmidt-Erfurth, Stephan, Michels, Irene, Barbazetto, Horst, Laqua   +3 more
openaire   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Comment to: Great saphenous vein surgery without high ligation of the saphenofemoral junction, by Casoni P, Lefebvre-Vilardebo M, Villa F, Corona P. J Vasc Surg 2013;58:173-8.

Veins and Lymphatics, 2014
Traditional surgical treatment of varicose disease requires an invasive procedure like high ligation of sapheno femoral junction (SFJ), resulting in high recurrence rates, especially in the long term. The aim of this prospective randomized study was to
Stefano Ricci
doaj   +1 more source

Coagulation-balance gene predictors influencing visual prognosis in patients treated with photodynamic therapy for classic choroidal neovascularization secondary to age-related macular degeneration. [PDF]

, 2010
PURPOSE: To determine whether different coagulation-balance genetic polymorphisms explain the variable clinical outcomes of photodynamic therapy with verteporfin (PDT-V) in Caucasian patients with classic or predominantly classic choroidal ...
Romano, Mario
core