Results 61 to 70 of about 16,236 (238)

A Bone Marrow–Mimetic Hydrogel Enables Dual‐Phase Hemostasis and Vascularized Osteogenesis for Cranial Defects

Advanced Science, EarlyView.
A biomimetic, fiber‐reinforced hydrogel (FE‐PDA@Fib/Gel‐TG) that enables dual‐phase cranial defect repair. The system provides: instant hemostasis in the early stage, and sustained co‐delivery of pro‐angiogenic and osteogenic signals for synergistic vascularized bone regeneration.
Lingbin Che, Donghong Li, Huan Zhang, Tingting Xu, Juhan Li, Xuanzhou Chen, Louis D. Zhang, Shuguang Wang, Dianwen Song, Dongyong Sha   +9 more
wiley   +1 more source

Blood Levels, Apoptosis, and Homing of the Endothelial Progenitor Cells After Skin Burns and Escharectomy

, 2011
BACKGROUND: Skin burns are an acute trauma involving an extensive vascular damage and an intense inflammatory response. Bone marrow-derived circulating endothelial progenitor cells (EPC) are known to migrate to sites of neovascularization in response to ...
VINDIGNI, VINCENZO, Francesco Mazzoleni, Carlo Foresta, Sabina Magagna, Vincenzo Vindigni, SCHIPILLITI M, MAGAGNA S, Bruno Azzena, FORESTA, CARLO, Luca De Toni, Mirko Schipilliti, DE TONI L, AZZENA B, MAZZOLENI F., Luca Lancerotto, LANCEROTTO L   +15 more
core   +1 more source

Endothelial differentiation of hematopoietic stem and progenitor cells from patients with multiple myeloma [PDF]

, 2008
Purpose: Vasculogenesis is a physiologic process typical of fetal development in which new blood vessels develop from undifferentiated precursors (or angioblasts).
Guarini A, PICCOLI, CLAUDIA, RIBATTI, Domenico, GUARINI A., Dammacco F, VACCA, Angelo, RIA, ROBERTO, DI RENZO N., GUIDOLIN D., Falzetti F, Cirulli T, Tabilio A, Vacca A., Ria R, TABILIO A., Mangialardi G, DAMMACCO F., GUIDOLIN, DIEGO, Piccoli C, FALZETTI F., CIRULLI T., Di Renzo N, GUIDOLIN D, PICCOLI C., Ribatti D, MANGIALARDI G.   +25 more
core   +1 more source

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

Advanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu, Meiqin Zhang, Ting Wu, Erfan Wei, Andrei Y. Hancharou, Zeying Wang, Zijuan Wang, Letian Lv, Likun Wu, Xingtong Pan, Qiyue Zhu, Xinyi Dong, Hao Liu, Yongsheng Zhou   +13 more
wiley   +1 more source

Optimizing the arterialized venous flap

, 2008
BACKGROUND: Outcome of arterialized venous flaps is quite varied. The authors' initial experiments showed that a good vascular bed contributes significantly to survival of the flap. In continuation of these experiments, this study aimed to understand the
Pittet Cuenod, Brigitte Maud, Mahajan, Ajay L., Schlaudraff, Kai-Uwe, Quinodoz, Pierre, Alizadeh, Navid   +4 more
core   +1 more source

Multi‐Axis Stretchable Zippers for Personalized Wound Healing

Advanced Science, EarlyView.
Multi‐axis stretchable zippers can adapt to complex wound morphologies and enable personalized wound treatment through programmable contraction. This morphological matching strategy helps accelerate wound closure, improve blood perfusion, promote epithelial regeneration, and enhance collagen remodeling, pioneering new directions for personalized and ...
Siyuan Cai, Guang Yao, Zijian Chen, Shiqi Zhou, Peisi Li, Liheng Lin, Huake Yang, Ziyi Zhou, Linbo Jin, Xingyi Gan, Chenzheng Zhou, Zhen Cai, Taisong Pan, Min Gao, Dongli Fan, Yuan Lin, Yiming Zhang   +16 more
wiley   +1 more source

Advances in BODIPY Derivatives for Antibacterial Phototherapy

Angewandte Chemie, EarlyView.
This review systematically summarizes the design strategies and structure‐activity relationships of BODIPY‐based antibacterial phototherapy, covering molecular engineering of small‐molecule photosensitizers and nanoplatforms, bacterial targeting and carrier design, and discussing the challenges and future perspectives associated with clinical ...
Li Lv, Heejeong Kim, Hongchen Zhai, Hanqi Ren, Silu Wang, Cong Sun, Yafu Wang, Hosoowi Lee, Juyoung Yoon, Hua Zhang   +9 more
wiley   +2 more sources

Human Dermal Microvascular Endothelial Cells Produce Matrix Metalloproteinases in Response to Angiogenic Factors and Migration

, 1995
Matrix metalloproteinases (MMPs) are a family of inducible enzymes that degrade extracellular matrix components, allowing cells to traverse connective tissue structures efficiently. Specific tissue inhibitors (TIMPs) function as physiologic inhibitors of
Leslie C. Nehring, Cornelius, Lynn A., Roby, Jill D., Howard G. Welgus, Nehring, Leslie C., Lynn A. Cornelius, Welgus, Howard G., Jill D. Roby, Parks, William C., William C. Parks   +9 more
core   +1 more source

Oxygen Vacancy‐Enriched Platinum Single‐Atom Nanozyme Wrapped in Nanoislands: Unlocking Catalytic Activity and Reprogramming Redox Microenvironment for Osteonecrosis Repair

Advanced Science, EarlyView.
CeO2‐x/Pt single‐atom nano‐island is constructed via low‐temperature reduction, featuring abundant oxygen vacancies and an island–sea structure. It delivers outstanding multi‐enzyme‐mimetic activity and ROS‐scavenging efficiency. Density functional theory reveals optimized electronic structures and reaction pathways.
Yang Zhu, Zehui Lv, Xuejie Cai, Penghui Wei, Dengliang Wang, Zhao Wang, Ruoying Wang, Yingjie Wang, Xingdong Yang, Yixin Bian, Jiawei Xu, Xisheng Weng, Liangfeng Wei   +12 more
wiley   +1 more source

Influence of the oxygen microenvironment on the proangiogenic potential of human endothelial colony forming cells [PDF]

, 2009
Therapeutic angiogenesis is a promising strategy to promote the formation of new or collateral vessels for tissue regeneration and repair. Since changes in tissue oxygen concentrations are known to stimulate numerous cell functions, these studies have ...
Chang I. Lee, Decaris, Martin L., Leach, J. Kent, Mervin C. Yoder, Alice F. Tarantal, Yoder, Mervin C., J. Kent Leach, Tarantal, Alice F., Lee, Chang I., Martin L. Decaris   +9 more
core   +1 more source