Results 21 to 30 of about 124,593 (307)

Endothelial progenitor cells in chronic obstructive pulmonary disease and emphysema.

PLoS ONE, 2017
Endothelial injury is implicated in the pathogenesis of COPD and emphysema; however the role of endothelial progenitor cells (EPCs), a marker of endothelial cell repair, and circulating endothelial cells (CECs), a marker of endothelial cell injury, in ...
Margaret F Doyle, Russell P Tracy, Megha A Parikh, Eric A Hoffman, Daichi Shimbo, John H M Austin, Benjamin M Smith, Katja Hueper, Jens Vogel-Claussen, Joao Lima, Antoinette Gomes, Karol Watson, Steven Kawut, R Graham Barr   +13 more
doaj   +1 more source

Single-Cell Transcriptional Profiling of Aortic Endothelium Identifies a Hierarchy from Endovascular Progenitors to Differentiated Cells

Cell Reports, 2019
Summary: The cellular and molecular profiles that govern the endothelial heterogeneity of the circulatory system have yet to be elucidated. Using a data-driven approach to study the endothelial compartment via single-cell RNA sequencing, we characterized
Samuel W. Lukowski, Jatin Patel, Stacey B. Andersen, Seen-Ling Sim, Ho Yi Wong, Joshua Tay, Ingrid Winkler, Joseph E. Powell, Kiarash Khosrotehrani   +8 more
doaj   +1 more source

Endothelial stem and progenitor cells (stem cells): (2017 Grover Conference Series)

Pulmonary Circulation, 2017
The capacity of existing blood vessels to give rise to new blood vessels via endothelial cell sprouting is called angiogenesis and is a well-studied biologic process.
Mervin C. Yoder
doaj   +1 more source

Transcriptomic Remodelling of Fetal Endothelial Cells During Establishment of Inflammatory Memory

Frontiers in Immunology, 2021
Inflammatory memory involves the molecular and cellular ‘reprogramming’ of innate immune cells following exogenous stimuli, leading to non-specific protection against subsequent pathogen exposure.
Elisa Weiss, Amanda Vlahos, Bowon Kim, Sachintha Wijegunasekara, Dhanya Shanmuganathan, Thomas Aitken, Thomas Aitken, Ji-Hoon E. Joo, Ji-Hoon E. Joo, Samira Imran, Samira Imran, Rebecca Shepherd, Jeffrey M. Craig, Jeffrey M. Craig, Jeffrey M. Craig, Mark Green, Ursula Hiden, Boris Novakovic, Boris Novakovic, Richard Saffery, Richard Saffery   +20 more
doaj   +1 more source

Single-cell RNA sequencing based analysis depicts the development map of human early embryonic erythrocytes [PDF]

Jichu yixue yu linchuang, 2022
Objective Single-cell RNA sequencing (scRNA-seq) was used to systematically delineate the cell atlas and molecular tracks of human early erythroid development at the single-cell level.
CHEN Zhong-yang, MA Yan-ni, YU Jia
doaj   +1 more source

Endothelial Progenitor Cells in Cerebrovascular Disease [PDF]

Stroke, 2005
To the Editor: In their interesting article, Ghani and colleagues reported a reduction in endothelial progenitor cells (EPCs) in patients with cerebrovascular disease, when compared with healthy control subjects.1 However, the authors did not mention a recent article by Taguchi et al reporting that CD34+ cells and CD133+ cells, as an EPC-enriched ...
FADINI, GIAN PAOLO, AGOSTINI, CARLO, AVOGARO, ANGELO   +2 more
openaire   +2 more sources

Human Endothelial Progenitor Cells [PDF]

Cold Spring Harbor Perspectives in Medicine, 2011
Human endothelial progenitor cells (EPCs) have been generally defined as circulating cells that express a variety of cell surface markers similar to those expressed by vascular endothelial cells, adhere to endothelium at sites of hypoxia/ischemia, and participate in new vessel formation.
openaire   +2 more sources

Endothelial Progenitor Cells in Diabetic Retinopathy [PDF]

Frontiers in Endocrinology, 2014
Diabetic retinopathy (DR) is a leading cause of visual impairment worldwide. Patients with DR may irreversibly lose sight as a result of the development of diabetic macular edema (DME) and/or proliferative diabetic retinopathy (PDR); retinal blood vessel dysfunction and degeneration plays an essential role in their pathogenesis. Although new treatments
Lois, Noemi, McCarter, Rachel V, O'Neill, Christina, Medina, Reinhold J, Stitt, Alan W   +4 more
openaire   +5 more sources

The Effects of HMG-CoA Reductase Inhibitor on Vascular Progenitor Cells

Journal of Pharmacological Sciences, 2006
.: Circulating bone marrow-derived vascular progenitor cells contribute to angiogenesis, atherosclerosis, and the response to vascular injury. These vascular progenitor cells consist of two cell groups, endothelial progenitor cells (EPCs) and smooth ...
Kusuyama Takanori, Omura Takashi, Nishiya Daisuke, Enomoto Soichiro, Matsumoto Ryo, Murata Takashi, Takeuchi Kazuhide, Yoshikawa Junichi, Yoshiyama Minoru   +8 more
doaj   +1 more source

Prehypertension and endothelial progenitor cell function [PDF]

Journal of Human Hypertension, 2010
Prehypertension is associated with significant damage to the coronary vasculature and increased rates of adverse cardiovascular events. Circulating endothelial progenitor cells (EPCs) are critical to vascular repair and the formation of new blood vessels. We tested the hypothesis that prehypertension is associated with EPC dysfunction. Peripheral blood
MacEneaney, OJ, DeSouza, C A, Weil, B R, Kushner, E J, Van Guilder, Gary, Mestek, M L, Greiner, J J, Stauffer, B L   +7 more
openaire   +2 more sources