Endothelial Progenitor Cells in Prehypertension
Blood pressure within prehypertensive levels confers higher cardiovascular risk. As prehypertension is also an intermediate stage for full hypertension, a precocious intervention with lifestyle changes or drugs is therefore appealing. Endothelial injury and dysfunction are thought to contribute to cardiovascular risk in prehypertension.
DI STEFANO, ROSSELLA +4 more
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Downregulation of ETS rescues diabetes-induced reduction of endothelial progenitor cells [PDF]
Background Transplantation of vasculogenic progenitor cells (VPC) improves neovascularization after ischemia. However, patients with type 2 diabetes mellitus show a reduced VPC number and impaired functional activity. Previously, we demonstrated that p38
Aicher Alexandra +17 more
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Endothelial progenitor cells in chronic obstructive pulmonary disease and emphysema.
Endothelial injury is implicated in the pathogenesis of COPD and emphysema; however the role of endothelial progenitor cells (EPCs), a marker of endothelial cell repair, and circulating endothelial cells (CECs), a marker of endothelial cell injury, in ...
Margaret F Doyle +13 more
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Summary: The cellular and molecular profiles that govern the endothelial heterogeneity of the circulatory system have yet to be elucidated. Using a data-driven approach to study the endothelial compartment via single-cell RNA sequencing, we characterized
Samuel W. Lukowski +8 more
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Transcriptomic Remodelling of Fetal Endothelial Cells During Establishment of Inflammatory Memory
Inflammatory memory involves the molecular and cellular ‘reprogramming’ of innate immune cells following exogenous stimuli, leading to non-specific protection against subsequent pathogen exposure.
Elisa Weiss +20 more
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Prostaglandin E Positively Modulates Endothelial Progenitor Cell Homeostasis: An Advanced Treatment Modality for Autologous Cell Therapy [PDF]
Aims: The mobilization of endothelial progenitor cells (EPC) and their functioning in postnatal neovascularization are tightly regulated. To identify new modulators of EPC homeostasis, we screened biologically active prostaglandin E compounds for their ...
Hermann, Patrick C. +6 more
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Single-cell RNA sequencing based analysis depicts the development map of human early embryonic erythrocytes [PDF]
Objective Single-cell RNA sequencing (scRNA-seq) was used to systematically delineate the cell atlas and molecular tracks of human early erythroid development at the single-cell level.
CHEN Zhong-yang, MA Yan-ni, YU Jia
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Endothelial Progenitor Cells in Cerebrovascular Disease [PDF]
To the Editor: In their interesting article, Ghani and colleagues reported a reduction in endothelial progenitor cells (EPCs) in patients with cerebrovascular disease, when compared with healthy control subjects.1 However, the authors did not mention a recent article by Taguchi et al reporting that CD34+ cells and CD133+ cells, as an EPC-enriched ...
FADINI, GIAN PAOLO +2 more
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Endothelial stem and progenitor cells (stem cells): (2017 Grover Conference Series)
The capacity of existing blood vessels to give rise to new blood vessels via endothelial cell sprouting is called angiogenesis and is a well-studied biologic process.
Mervin C. Yoder
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The Effects of HMG-CoA Reductase Inhibitor on Vascular Progenitor Cells
.: Circulating bone marrow-derived vascular progenitor cells contribute to angiogenesis, atherosclerosis, and the response to vascular injury. These vascular progenitor cells consist of two cell groups, endothelial progenitor cells (EPCs) and smooth ...
Kusuyama Takanori +8 more
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