Results 41 to 50 of about 124,593 (307)

Transdifferentiation of endothelial progenitor cells into rhabdomyosarcoma defined by hedgehog signaling competence

Cell Reports
Summary: Rhabdomyosarcoma (RMS) is a pediatric soft tissue sarcoma resembling developing skeletal muscle, but tumors are found in sites devoid of skeletal muscle, suggesting a non-myogenic cell of origin. We previously described an endothelial progenitor
Katherine E. Gadek, Catherine J. Drummond, Hongjian Jin, Matthew R. Garcia, Edwin D. Mathew, Grace E. Adkins, Casey G. Langdon, Myron Evans, Madeline B. Searcy, Patrick Schreiner, Matthew Maguire, Jerold E. Rehg, Stacey K. Ogden, Mark E. Hatley   +13 more
doaj   +1 more source

Inducible Forward Programming of Human Pluripotent Stem Cells to Hemato-endothelial Progenitor Cells with Hematopoietic Progenitor Potential

Stem Cell Reports, 2020
Summary: Induced pluripotent stem cells (iPSCs) offer a promising platform to model early embryonic developmental processes, to create disease models that can be evaluated by drug screens as well as proof-of-concept experiments for regenerative medicine.
Lucas Lange, Dirk Hoffmann, Adrian Schwarzer, Teng-Cheong Ha, Friederike Philipp, Daniela Lenz, Michael Morgan, Axel Schambach   +7 more
doaj   +1 more source

Endothelial progenitor cells and atherosclerosis

Frontiers in Bioscience, 2013
Atherosclerosis is due to inflammation and endothelial dysfunction and damage caused by a variety of factors. Dysfunction of endothelial progenitor cells (EPCs) that differentiate into mature endothelial cell contributes to the development of atherosclerosis.
Changwu, Ruan, Yan, Shen, Rui, Chen, Zhancheng, Wang, Jin, Li, Yun, Jiang   +5 more
openaire   +2 more sources

Aberrant lymphatic endothelial progenitors in lymphatic malformation development.

PLoS ONE, 2015
Lymphatic malformations (LMs) are vascular anomalies thought to arise from dysregulated lymphangiogenesis. These lesions impose a significant burden of disease on affected individuals.
June K Wu, Christopher Kitajewski, Maia Reiley, Connie H Keung, Julie Monteagudo, John P Andrews, Peter Liou, Arul Thirumoorthi, Alvin Wong, Jessica J Kandel, Carrie J Shawber   +10 more
doaj   +1 more source

Circulating progenitor cell count for cardiovascular risk stratification: a pooled analysis [PDF]

, 2010
Background: Circulating progenitor cells (CPC) contribute to the homeostasis of the vessel wall, and a reduced CPC count predicts cardiovascular morbidity and mortality.
Zeiher Andreas M., ZEIHER AM, Saula de Kreutzenberg, Ozaki Takenori, MARUYAMA S, Schmidt-Lucke, Caroline, Andreas M. Zeiher, Takenori Ozaki, Schmidt-Lucke Caroline, Avogaro, Angelo, WERNER N., Meigs, James, Nikos Werner, Meigs James, SCHMIDT LUCKE C, VIGILI DE KREUTZENBERG, SAULA, Shoichi Maruyama, Werner, Nikos, Fadini, Gian Paolo, Nickenig, Georg, OZAKI T, Taguchi Akihiko, DIMMELER S, Caroline Schmidt-Lucke, Werner Nikos, Taguchi, Akihiko, Andreas M Zeiher, MEIGS J, NICKENIG G, Maruyama Shoichi, Angelo Avogaro, Ozaki, Takenori, Gian Paolo Fadini, Fadini Gian Paolo, TAGUCHI A, Dimmeler Stefanie, Stefanie Dimmeler, Dimmeler, Stefanie, De Kreutzenberg, Saula, Maruyama, Shoichi, Akihiko Taguchi, Zeiher, Andreas M., James Meigs, Nickenig Georg, Avogaro Angelo, Georg Nickenig, de Kreutzenberg Saula   +46 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A Case of Abnormal Lymphatic-Like Differentiation and Endothelial Progenitor Cell Activation in Neovascularization Associated with Hemi-Retinal Vein Occlusion

Case Reports in Ophthalmology, 2015
Purpose: Pathological vascular differentiation in retinal vein occlusion (RVO)-related neovessel formation remains poorly characterized. The role of intraocular lymphatic-like differentiation or endothelial progenitor cell activity has not been studied ...
Sirpa Loukovaara, Erika Gucciardo, Pauliina Repo, Jouko Lohi, Petri Salven, Kaisa Lehti   +5 more
doaj   +1 more source

Improved arteriogenesis with simultaneous skeletal muscle repair in ischemic tissue by SCL plus multipotent adult progenitor cell clones from peripheral blood [PDF]

, 2004
Background: The CD34- murine stem cell line RM26 cloned from peripheral blood mononuclear cells has been shown to generate hematopoietic progeny in lethally irradiated animals.
Seliger, Christian, Huss, Ralf, Kinston, Sarah, Gottgens, Berthold, Heil, Matthias, Sabine Moosmann, Matthias Heil, Christian Seliger, Sabine Sagebiel, Berthold Gottgens, Tibor Ziegelhoeffer, Moosmann, Sabine, Ralf Huss, Sarah Kinston, Ziegelhoeffer, Tibor, Sagebiel, Sabine   +15 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Human endothelial-like differentiated precursor cells maintain their endothelial characteristics when cocultured with mesenchymal stem cell and seeded onto human cancellous bone [PDF]

, 2013
Introduction. Cancellous bone is frequently used for filling bone defects in a clinical setting. It provides favourable conditions for regenerative cells such as MSC and early EPC.
Marzi, Ingo, Dirk Henrich, Barker, John Howard, John Barker, Cancellous Bone, Henrich, Dirk, Ingo Marzi, Seebach, Caroline, Joerg Warzecha, Caroline Seebach, Wilhelm, Kerstin, Warzecha, Jörg, Frank, Johannes, Kerstin Wilhelm, Johannes Frank   +14 more
core   +1 more source