Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li +9 more
wiley +1 more source
Preconditioning With TGF-β Inhibitors Enhances Therapeutic Efficacy of Endothelial Progenitor Cells for Wound Healing in Diabetic Mice. [PDF]
Su D +12 more
europepmc +1 more source
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
AGGF1-primed endothelial progenitor cells alleviate ischaemia-reperfusion injury in diabetic hearts. [PDF]
Li X +9 more
europepmc +1 more source
Neuroinflammation alters blood–brain barrier integrity and contributes to neurological disorders, yet existing models lack human immune complexity. This study presents a 3D, immune‐responsive platform that reconstructs key neurovascular components and enables real‐time monitoring.
Pavlo Gordiichuk +9 more
wiley +1 more source
Human placenta-derived endothelial progenitor cells: an animal-free culture system for efficient expansion. [PDF]
Yuan S +7 more
europepmc +1 more source
Foxc1 regulates Pecam-1 Expression in embryonic Endothelial Progenitor Cells [PDF]
Lamparter, Mathias
core
Transcriptomic profiling of endothelial progenitor cells in post-COVID-19 patients: Insights at 3 and 6-month post-infection. [PDF]
Poyatos P +8 more
europepmc +1 more source
Endothelial progenitor cells in pregnancy-related diseases. [PDF]
Chen Y +6 more
europepmc +1 more source

