Results 261 to 270 of about 5,302,488 (329)

[Retracted] Antiproliferation effect of the uremic toxin <i>para</i>‑cresol on endothelial progenitor cells is related to its antioxidant activity. [PDF]

Mol Med Rep
Pan L, Ye X, Ding I, Zhou Y.
europepmc   +1 more source

Genomics and epigenomics of tissue repair: Implications for personalized medicine

Precision Medical Sciences, EarlyView.
Genomic and epigenomic mechanisms govern tissue repair and regeneration through dynamic regulation of inflammation, cell fate, and extracellular matrix remodeling. The integration of multi‐omics, artificial intelligence, and precision regenerative therapies enables biomarker‐driven, personalized approaches to enhance healing and minimize fibrosis ...
Jharna Medhi, Chandrashekar Thalluri, Sarad Pawar Naik Bukke, Piyali Dey, Mallikarjun Vasam, Ananda Kumar Chettupalli, Swetha Kumari Koduru, Gali Avinash Kumar   +7 more
wiley   +1 more source

Decreased Endothelial Progenitor Cells Are Associated with Severe Coronary Artery Disease: Insights from a Clinical Study. [PDF]

J Cardiovasc Dev Dis
Tomić I, Zeljko I, Brizić I, Šoljić V, Ivančić I, Tomić M, Ćurlin M, Tomić D.   +7 more
europepmc   +1 more source

Precise delineation of radiation targets for thoracic tumors in the immunotherapy era: from immune mechanisms to clinical practice

Precision Radiation Oncology, EarlyView.
RT‐immunotherapy synergy for thoracic tumors relies on precise target delineation to protect immune components. IFI, reduced volumes, and optimized positioning minimize damage, while multimodal imaging, DL, PBT, and FLASH‐RT enhance control. These innovations shift RT to an immune‐centric model, improving lung and esophageal cancer outcomes.
Xiaoying Chen, Minxiao Yi, Yu Deng, Qian Shen   +3 more
wiley   +1 more source

Endothelial progenitor cells for diabetic cardiac and kidney disease. [PDF]

Stem Cells Transl Med
Raleigh MJ, Pasricha SV, Nauth A, Ward MR, Connelly KA.   +4 more
europepmc   +1 more source

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Age-Related Choroidal Involution Is Associated with the Senescence of Endothelial Progenitor Cells in the Choroid. [PDF]

Biomedicines
Nazari AR, Gresseau L, Habelrih T, Zia A, Lahaie I, Er-Reguyeg Y, Coté F, Annabi B, Rivard A, Chemtob S, Desjarlais M.   +10 more
europepmc   +1 more source

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source

Circulating Endothelial Progenitor Cells in Patients with Established Cardiovascular Disease Treated with PCSK9 Monoclonal Antibodies. [PDF]

Am J Prev Cardiol
Gurevitz C, Zadok OIB, Leshem-Lev D, Hodeda L, Rotholz A, Kornowski R, Eisen A.   +6 more
europepmc   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source