Results 141 to 150 of about 21,304,051 (308)

Can Endothelin-1 Levels in Patients with Esophageal Variceal Bleeding at Admission Predict Rebleeding Within 5 Days?

Background/Aims: Portal hypertension complicating liver cirrhosis is associated with vascular resistance, possibly due to overexpression of humoral vasoconstrictors, including endothelin.
Metwaly Ibrahim Mortada, Ahmed I. Amin, A. El Messery, Mostafa H. Elshennawy, Ahmed Elshabrawi, Hatem Elalfy, Dina Elhammady, Shaker Wagih Shaltout, Walid ElSherbiny   +8 more
core   +1 more source

Plasma Endothelin-1 In Nigerian Hypertensives

, 2018
Background: Essential hypertension is characterized by endothelial dysfunction and increased peripheral resistance; the main constricting factors being endothelin - 1(ET-1).It may be expected that an abundance of constricting factors should be prevalent ...
Adebola, Phillips.A, Folasade, Daniel A, Ekun, Ayodele.O   +2 more
core   +1 more source

Menopause and vascular endothelial health: Is it all about the oestrogen?

Experimental Physiology, EarlyView.
Abstract Cardiovascular disease (CVD) is a leading cause of mortality in women, and CVD risk is accelerated during the menopause transition. This acceleration has traditionally been attributed to the hallmark decline in oestradiol with menopause. However, the menopause transition is also characterized by changes in other sex hormones that exert effects
Virginia R. Nuckols, Allyson I. Schwab, Lyndsey E. DuBose, Kerrie L. Moreau, Megan M. Wenner   +4 more
wiley   +1 more source

Contributions of vascular ageing to late‐onset Alzheimer's disease

Experimental Physiology, EarlyView.
Abstract Late‐onset Alzheimer's disease (LOAD) is an age‐related disease that is strongly associated with vascular risk factors and cerebrovascular impairments. As such, changes in the vasculature with advancing age likely contribute to LOAD, but the mechanisms underlying these contributions remain incompletely understood.
Skylyn J. Ferguson, Young Deanna Choi, Ashley E. Walker   +2 more
wiley   +1 more source

Endothelin-1 Immunoreactivity in plasma is elvated in HIV-1 infected patients with Retinal Microangiopathic syndrome [PDF]

, 1994
Bogner, Johannes R., Klauss, Volker, Rolinski, B., Geier, Stephan A., Sadri, Ifna, Goebel, Frank-Detlef, Ehrenreich, H.   +6 more
core   +1 more source

VEGF inhibitor‐induced vascular dysfunction involves redox‐sensitive PARP activation and SIRT1 disruption

Experimental Physiology, EarlyView.
Abstract Vascular endothelial growth factor receptor (VEGFR) inhibitors are effective antiangiogenic agents used in cancer therapy. However, they are associated with cardiovascular disease, including hypertension and vascular dysfunction. The molecular mechanisms underlying these cardiovascular toxicities are unclear, but oxidative stress might be ...
Karla B. Neves, Rheure Alves‐Lopes, Augusto C. Montezano, Rhian M. Touyz   +3 more
wiley   +1 more source

Preferential recruitment of neutrophils by endothelin-1 in acute lung inflammation induced by lipopolysaccharide or cigarette smoke

, 2008
Tapan Bhavsar, Xing Jian Liu, Hardik Patel, Ralph Stephani, Jerome O CantorSt John’s University, School of Pharmacy and Allied Health Sciences, New York, USAAbstract: This study examined the role of endothelin-1 (ET-1) in recruiting ...
Jerome O Cantor, Hardik Patel, Xing Jian Liu, Tapan Bhavsar, Ralph Stephani   +4 more
core  

Passive hyperthermia increases blood circulation in specific regions, largely independent of conduit artery mechanics and cardiac performance

Experimental Physiology, EarlyView.
Abstract Passive hyperthermia increases net peripheral and systemic blood flow in humans and other animals, yet the underlying haemodynamic forces that selectively accelerate blood movement remain incompletely characterized. Wave intensity analysis offers insight into the respective contributions of the heart and the vascular system to changes in blood
Nuno Koch Esteves, Kazuhito Watanabe, Francesca R. Cavallo, Ashraf W. Khir, José González‐Alonso   +4 more
wiley   +1 more source

Endothelin-1 [PDF]

, 2020
openaire   +1 more source

Eight weeks of high‐intensity interval training is insufficient to prevent sitting‐induced endothelial dysfunction and microvascular impairment

Experimental Physiology, EarlyView.
Abstract Prolonged sitting disrupts lower‐limb endothelial and microvascular function, likely via reduced shear stress and blunted microvascular reactivity. We examined whether Tabata‐style high‐intensity interval training (HIIT) mitigates this sitting‐induced vascular dysfunction.
Nobukazu Kasai, Hayato Ihara, Motoyuki Iemitsu, Takuma Morishima   +3 more
wiley   +1 more source