Results 231 to 240 of about 21,304,051 (308)

Heparanase inhibition prevents glycocalyx damage and albuminuria in experimental minimal change disease

open access: yes
Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
Michael Crompton   +18 more
wiley   +1 more source

GRKs and arrestins: Nomenclature and functions in GPCR‐dependent and ‐independent signalling

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 11, Page 2619-2633, June 2026.
G protein‐coupled receptor (GPCR) kinases (GRKs) and arrestins play a critical role in the regulation of GPCR signalling. Historic names of mammalian GRKs were replaced by systematic ones in the 1990s; however, both kinds of names are currently in use for mammalian arrestins.
Vsevolod V. Gurevich
wiley   +1 more source

Endothelin-1 triggers oxidative stress and cytokine release in human microglia cells through ETRB-dependent mechanisms. [PDF]

open access: yesFront Cell Neurosci
Inostroza-Nieves Y   +6 more
europepmc   +1 more source

Cardiovascular Health in Women—Across the Lifespan

open access: yesClinical Endocrinology, Volume 104, Issue 6, Page 539-555, June 2026.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar   +5 more
wiley   +1 more source

A Comprehensive Echocardiographic Assessment of Patients With Chronic Myeloid Leukemia on Dasatinib

open access: yesEchocardiography, Volume 43, Issue 6, June 2026.
In a retrospective cohort of 199 adult patients with CML on Dasatinib in a single quaternary center, approximately 25% patients had routine baseline and follow‐up echocardiogram. Dasatinib was associated with significant changes in structural and diastolic parameters.
Chen Chen   +4 more
wiley   +1 more source

Integrative Genomics Identifies Candidate Genes Underlying Trypanotolerance in Hybrid African Cattle

open access: yesEvolutionary Applications, Volume 19, Issue 6, June 2026.
ABSTRACT Integrative genomics combines data from different omics sources to link genotypes and phenotypes with the aim of unravelling biological networks and pathways that undergird complex traits, particularly with respect to disease. In this respect, integrative genomics, leveraging population and functional genomic data, can be employed to ...
Gillian P. McHugo   +10 more
wiley   +1 more source

Integrative Advances in Equine Genomics From Reference Assemblies to Evolutionary History and Key Traits

open access: yesEvolutionary Applications, Volume 19, Issue 6, June 2026.
ABSTRACT Horses are major domestic animals and cultural symbols that have accompanied humans for millennia. They underpin transport, agriculture, warfare and sport, and also provide a model for studying domestication, complex traits and adaptive evolution.
Ying Lu   +6 more
wiley   +1 more source

EWAS in COPD by biomass-burning smoke exposure identifies low levels of endothelin-1 by hypermethylation of EDN1. [PDF]

open access: yesEpigenomics
García-Carmona S   +11 more
europepmc   +1 more source

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