Circadian Clock Regulates Epidermal Endocrine System in Homeostatic Skin Pigmentation
ABSTRACT The circadian clock regulates multiple physiological processes in the skin, including local hormone synthesis and pigmentation. However, how circadian regulation interacts with epidermal endocrine signalling in melanocytes remains unclear.
Anya Zhu +5 more
wiley +1 more source
Prognostic Value of Plasma Big Endothelin-1 in Patients Hospitalized for Heart Failure. [PDF]
Wang J +9 more
europepmc +1 more source
Abstract Background Chronic kidney disease (CKD) is a significant public health challenge in Australia, affecting ~10% of the adult population and contributing to substantial morbidity and mortality. Diabetes, hypertension, cardiovascular disease and CKD frequently co‐exist; therefore, a multidisciplinary approach is necessary to manage these ...
M. P. Schlaich +7 more
wiley +1 more source
Long term safety and efficacy of a functionalized nanogel with endothelin-1 and bradykinin receptor antagonist peptides for treatment of osteoarthritis of the metacarpophalangeal and distal interphalangeal joints in horses: a descriptive clinical pilot study. [PDF]
Terlinden A +15 more
europepmc +1 more source
ABSTRACT Aim To clarify the molecular mechanisms of occlusal trauma in bone loss through periodontal tissue transcriptome analysis in mice with periodontitis and traumatic occlusion. Materials and Methods Ligature‐induced periodontitis (Li) and composite resin‐induced traumatic occlusion (Tra) mouse models were established (control [Co], Li, Tra and ...
Yosuke Tsuchiya +7 more
wiley +1 more source
Subclinical myocardial dysfunction in normoglycemic first-degree relatives of patients with type 2 diabetes mellitus: Associations with Endothelin-1, E-selectin, and Endocan. [PDF]
Çulcuoğlu İ +7 more
europepmc +1 more source
ABSTRACT Background Hyperpigmentation disorders are a distressing condition, especially for individuals with skin of color who are at higher risk. Often treated topically, a significant advancement in this field was Kligman's depigmenting trio, inhibiting melanogenesis, providing anti‐inflammatory benefits, and promoting epidermal renewal.
Susanna Margaretha H. Kannenberg +9 more
wiley +1 more source
Protective Effects of Panax ginseng Extract on Endothelin-1- and Isoproterenol-Induced Cardiac Hypertrophy via Maintenance of Mitochondrial Function and Calcium-Reactive Oxygen Species (ROS) Homeostasis. [PDF]
Tagashira H +3 more
europepmc +1 more source
Abstract Sitting‐induced impairments in postprandial blood flow are an important link between sedentary behaviour and cardiometabolic disease risk. The objective of this work was to examine the effects of resistance exercise breaks (REB) performed every 30 min during an otherwise sedentary 3‐h period on the vasodilatory response to a subsequent oral ...
Emily M. Rogers +8 more
wiley +1 more source

