Effect of Endothelin-1 on the Excitability of Rat Cortical and Hippocampal Slices In Vitro
R. Konopková +4 more
openalex +1 more source
Current Status of Research on Losartan in Tumour Therapy
ABSTRACT Losartan, a widely prescribed antihypertensive agent, has attracted growing interest as a potential adjuvant in cancer therapy due to its affordability, established safety profile and pleiotropic effects. Emerging preclinical evidence demonstrates that losartan can effectively modulate the tumour microenvironment (TME) by inhibiting ...
Han Wang, Shuang Yuan, Hongjing Wang
wiley +1 more source
The metabolism of big endothelin-1 axis and lipids affects carotid atherosclerotic plaque stability - the possible opposite effects of treatment with statins and aspirin. [PDF]
Płoński A +8 more
europepmc +1 more source
Spatial Transcriptomic Assessments of Gene Expression Profiles in Human Peri‐Implant Lesions
ABSTRACT Aim To analyse gene expression profiles in human tissue samples obtained from dental implant sites with or without peri‐implantitis. Materials and Methods Soft‐tissue biopsy samples obtained from patients presenting with implants with severe peri‐implantitis and adjacent reference implants with no signs of peri‐implantitis were analysed by ...
C. Dionigi +4 more
wiley +1 more source
Plasma Endothelin-1 Levels: Non-Predictors of Alzheimer's Disease Reveal Age Correlation in African American Women. [PDF]
Zagol-Ikapitte IA +3 more
europepmc +1 more source
Targeting Melasma: Innovations in Pigment Deposition and Photoaging in Cosmetic Dermatology
ABSTRACT Background Melasma is a chronic, relapsing hyperpigmentation disorder driven by complex interactions among genetic predisposition, hormonal fluctuations, UV exposure, oxidative stress, inflammation, and photoaging. Its psychosocial impact is substantial, especially among women with darker skin types, and treatment remains challenging due to ...
Ting Liao +4 more
wiley +1 more source
Post-stroke butyrate treatment shows sex-dependent microglial responses but does not improve outcomes in a mouse model of endothelin-1 sensory motor stroke. [PDF]
de Witte A +10 more
europepmc +1 more source
ABSTRACT Microvascular inflammation (MVI) in kidney allografts in the absence of detectable donor‐specific anti‐HLA antibodies (DSA) is increasingly recognised as a cause of premature graft failure following kidney transplantation. Potential mechanisms include NK cell alloreactivity mediated by recognition of mismatched HLA class I molecules (missing ...
Laura Knödl +8 more
wiley +1 more source

