Results 321 to 330 of about 23,747,035 (396)

Dual ETA‐ETB receptor antagonism improves metabolic syndrome‐induced heart failure with preserved ejection fraction

Fundamental &Clinical Pharmacology, Volume 39, Issue 3, June 2025.
Abstract Background Metabolic syndrome (MetS) is a multifaceted disease associated with heart failure (HF), which affects the vascular system. The endothelin (ET) system is a key player in MetS and HF; therefore, targets for ET receptors are of therapeutic interest.
Francesca Lockwood, Marianne Lachaux, Najah Harouki, Matthieu Soulié, Lionel Nicol, Sylvanie Renet, Anaïs Dumesnil, Magali Vercauteren, Jeremy Bellien, Marc Iglarz, Vincent Richard, Paul Mulder   +11 more
wiley   +1 more source

Endothelin-1 Plasma and Aqueous Humor Levels in Different Types of Glaucoma: A Systematic Review and Meta-Analysis. [PDF]

Medicina (Kaunas)
Lampsas S, Kandarakis SA, Vakalopoulos DG, Lampsa A, Oikonomou E, Siasos G, Kymionis GD.   +6 more
europepmc   +1 more source

Cardioprotective and Anti‐Hypertensive Effects of Epigallocatechin Gallate: Novel Insights Into Biological Evidence

The Journal of Clinical Hypertension, Volume 27, Issue 6, June 2025.
ABSTRACT Epigallocatechin gallate (EGCG), the major catechin in green tea, is of considerable interest principally due to its proposed antihypertensive and cardioprotective properties. New research shows that EGCG can help relax the circulation of blood vessels, reduce arterial stiffness of arteries, and promote antioxidant activity promotion, which ...
Reza Eshraghi, Ashkan Bahrami, Faraz Tayyar Iravanlou, Mehdi Karimi, Mohammad Saeed Soleimani, Mohammad Hossein Paknahad, Mohammad Yaghoubi, Arman Beheshtirooy, Fatemeh Qasemi Talouki, Javad Shaabanzadeh, Fatemeh Hasani, Alireza Rafi, Mohammad Hossein Pourhanifeh   +12 more
wiley   +1 more source

The endothelin-1-driven tumor-stroma feed-forward loops in high-grade serous ovarian cancer. [PDF]

Clin Sci (Lond)
Tocci P, Roman C, Sestito R, Caprara V, Sacconi A, Molineris I, Tonon G, Blandino G, Bagnato A.   +8 more
europepmc   +1 more source

Plant‐Derived Monomers for Grey Hair Reversal Through Upregulation of Melanogenesis and Tyrosinase Activity

Journal of Cellular and Molecular Medicine, Volume 29, Issue 11, June 2025.
ABSTRACT Grey hair, a common ageing‐associated phenomenon in humans, is mainly attributed to the damage of melanocytes and the absence of melanin. Grey hair has long been treated with traditional medicine, and new research has shown that various plant‐derived monomers can increase tyrosinase activity and melanogenesis, indicating that they may have ...
Chengjie Wei, Xiaomin Hou, Xuelu Jiang, Ming Gao, Yan Gao, Lin Bi, Jisheng Nie, Liangyuan Zhao, Yiwei Shi, Xiaojiang Qin   +9 more
wiley   +1 more source

Wound, pressure ulcer, and burn guidelines (2023)―4: Guidelines for the management of connective tissue disease/vasculitis‐associated skin ulcers, third edition

The Journal of Dermatology, Volume 52, Issue 6, Page e430-e480, June 2025.
Yoshihide Asano, Jun Asai, Takayuki Ishii, Yohei Iwata, Masanari Kodera, Chie Miyabe, Akihiko Uchiyama, Youichi Ogawa, Ken Okamura, Mari Kishibe, Yuta Koike, Yorihisa Kotobuki, Noriki Fujimoto, Takuya Miyagi, Yukie Yamaguchi, Ayumi Yoshizaki, Reiko Omori, Takeshi Nakanishi, Hiroshi Fujiwara, Takeo Maekawa, Sei‐ichiro Motegi, Yuichiro Yoshino, Minoru Hasegawa, Manabu Fujimoto, Takao Tachibana, Wound, Pressure Ulcer, and Burn Guidelines Drafting Committee (connective tissue disease/vasculitis group)   +27 more
wiley   +1 more source

Multiomics‐Driven Drug‐Cell Interaction Network for Chemotherapy Sensitivity Prediction in Metabolically Defined Triple‐Negative Breast Cancer Subtypes

Journal of Cellular and Molecular Medicine, Volume 29, Issue 11, June 2025.
ABSTRACT Triple‐negative breast cancer (TNBC) is associated with a poor prognosis due to insufficient molecular subtyping precision and limited actionable targets. Although metabolic reprogramming underlies TNBC chemotherapy resistance, establishing metabolic subtyping systems and investigating drug sensitivity across distinct metabolic subgroups could
Jingyuan Zhang, Xuejun Sun
wiley   +1 more source

The role of transient receptor potential melastatin channels in compressive force‐induced contraction of primary cardiac pericytes

Physiological Reports, Volume 13, Issue 12, June 2025.
Abstract Pericytes contract during acute myocardial infarction (AMI) resulting in capillary constriction, which further contributes to the ischemic damage and enlargement of infarct size. We hypothesized that increased intramyocardial pressure during ischemia can be sensed by mechanosensitive Transient Receptor Potential (TRP) channels in cardiac ...
Carmen Methner, Eugene Cilento, Zhiping Cao, Jeffrey Iliff, Anusha Mishra, Sanjiv Kaul   +5 more
wiley   +1 more source

Evaluation of the serum levels of endothelin-1 and lipid profile in chronic periodontitis patients, before and after periodontal therapy.

J Indian Soc Periodontol
Desingu V, Ravi S, Balagangadharan M, Nagarajan S, Kesavan P, Ramalingam K.   +5 more
europepmc   +1 more source