Results 201 to 210 of about 40,821 (327)

Subcutaneous Treprostinil in PH Associated With Left Heart Disease or Chronic Lung Disease

Pulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Pulmonary hypertension (PH) associated with left heart disease (LHD‐PH) and pulmonary hypertension associated with chronic lung disease (CLD‐PH) are the most common PH subtypes but lack effective treatments. In a prospective cohort study, 90 patients (39 LHD‐PH, 51 CLD‐PH) with severe disease [pulmonary vascular resistance (PVR) > 5 Wood units
Roela Sadushi‐Koliçi, Leila Alajbegovic, Vladimir Gojic, Nika Skoro‐Sajer, Ioana Campean, Inbal Shafran, Deddo Mörtl, Christian Gerges, Irene M. Lang   +8 more
wiley   +1 more source

Can Combination Therapy with Endothelin Receptor Antagonist and PDE5 Inhibitors Prevent Echocardiographic Findings Suspicious for Pulmonary Arterial Hypertension? Description of a Real-Life Case Series. [PDF]

Diagnostics (Basel)
Damiani A, Lepri G, Bonomi F, Fiorentini E, Peretti S, Blagojevic J, Bellando Randone S, Guiducci S.   +7 more
europepmc   +1 more source

Pharmacological Profile in vitro of A New Endothelin Receptor Antagonist, TAK-044.

, 1994
Yumiko Awane, Keiji Kusumoto, Kazuki Kubo, Akira Kawata, Takashi Kikuchi, Mitsyhiro Wakimasu, Toshifumi Watanabe, Masahiko Fujino   +7 more
openalex   +1 more source

SERAPHIN haemodynamic substudy: the effect of the dual endothelin receptor antagonist macitentan on haemodynamic parameters and NT-proBNP levels and their association with disease progression in patients with pulmonary arterial hypertension [PDF]

, 2017
Nazzareno Galiè, Pavel Jansa, Tomás Pulido, Richard N. Channick, Marion Delcroix, Hossein Ardeschir Ghofrani, Franck‐Olivier Le Brun, Sanjay Mehta, Loı̈c Perchenet, Lewis J. Rubin, B.K.S. Sastry, Gérald Simonneau, Olivier Sitbon, Rogério Souza, Adam Torbicki   +14 more
openalex   +1 more source

Methamphetamine‐Associated Pulmonary Arterial Hypertension: Impact, Mechanisms, and a Framework for Management

Pulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Methamphetamine‐associated pulmonary arterial hypertension (Meth‐PAH) is an increasingly prevalent but understudied subtype of Group 1 pulmonary arterial hypertension (PAH). While most prevalent in the Western United States, its reach continues to expand with the evolving global methamphetamine epidemic.
Namita Sood, Jonika Weerasekare, Iryna Zhyvylo, Elena A. Goncharova, Teresa De Marco   +4 more
wiley   +1 more source

Sustained effect of macitentan, a novel oral endothelin receptor antagonist, on exercise capacity and the association of its measure with long-term outcomes in pulmonary arterial hypertension [PDF]

, 2013
Nazzareno Galiè, Richard N. Channick, Marion Delcroix, Hossein Ardeschir Ghofrani, Pavel Jansa, F Brun, G. Simonneau, Lewis J. Rubin   +7 more
openalex   +1 more source

Transmembrane Protein 100 Expression on Endothelial Cells Vascularizing Thrombi in Chronic Thromboembolic Pulmonary Hypertension Modulates TGFβ1−ALK1 Signaling During Angiogenesis

Pulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Endothelial cells within chronic pulmonary artery thrombi in CTEPH overexpress transmembrane protein 100 (TMEM100), an activin A receptor‐like kinase 1 (ACVRL1 or ALK1) signaling‐dependent gene, and TGFβ1 upregulated TMEM100 transcription in healthy lung ECs.
Magdalena L. Bochenek, Iman Ghasemi, Christoph B. Wiedenroth, Olympia Bikou, Ioannis Karampinis, Eric D. Roessner, Lukas Hobohm, Stefan Guth, Philipp Lurz, Stavros Konstantinides, Katrin Schäfer   +10 more
wiley   +1 more source

The Clinical Course of Portopulmonary Hypertension and Outcomes With Endothelin Receptor Antagonist Treatment: Observational Study of Data From the US Organ Procurement and Transplantation Network. [PDF]

Transplant Direct
DuBrock HM, Jose A, Arendse S, Martin N, Studer S, Rosenberg D.   +5 more
europepmc   +1 more source

Selection of Endothelin Receptor Antagonists in the Treatment of Pulmonary Arterial Hypertension: A Comprehensive Narrative Review [PDF]

Naomi Habib, ANKITA ADHIA, David López, Marinella Sandros, P Guichard   +4 more
openalex   +1 more source

Isolated Anti‐SS‐A Antibody Seropositivity as a Poor Prognostic Factor in Systemic Sclerosis: Insights From a Cohort of 307 Cases

The Journal of Dermatology, Volume 53, Issue 1, Page 41-53, January 2026.
ABSTRACT Systemic sclerosis is an autoimmune disease characterized by vasculopathy, fibrosis, and immune dysregulation. Anti‐SS‐A antibodies (anti‐SSA) have been reported to confer severe clinical manifestations in some Western and Japanese cohorts. We aimed to determine whether anti‐SSA seropositivity affects clinical outcomes in Japanese patients. We
Nana Ishida, Kazuki M. Matsuda, Hirohito Kotani, Hayakazu Sumida, Shinichi Sato   +4 more
wiley   +1 more source