Results 201 to 210 of about 18,452 (302)

Rare but relevant: The injection of tablet preparations and pulmonary hypertension

Addiction, Volume 120, Issue 6, Page 1276-1279, June 2025.
Abstract Intravascular injection of dissolved medicinal preparations such as crushed tablets is associated with a risk of injecting particulate material into the vasculature. This particulate material will naturally pass to the lungs where it will be largely filtered out in the pulmonary vascular bed, and in turn, it can result in a range of ...
Johan Duflou
wiley   +1 more source

The protective effect of endothelin receptor antagonists against surgically induced impairment of gastrointestinal motility in rats. [PDF]

J Smooth Muscle Res, 2019
Ługowska-Umer H, Umer A, Kuziemski K, Sein-Anand Ł, Korolkiewicz RP.   +4 more
europepmc   +1 more source

Carbazolothiophene-2-carboxylic acid derivatives as endothelin receptor antagonists [PDF]

, 2004
G. Suresh Babu, Hui‐Ming Yu, Shyh‐Ming Yang, Jim‐Min Fang   +3 more
openalex   +1 more source

SorCS2 Is Important for Astrocytic Function in Neurovascular Signaling

Acta Physiologica, Volume 241, Issue 6, June 2025.
ABSTRACT Introduction The receptor SorCS2 is involved in the trafficking of membrane receptors and transporters. It has been implicated in brain disorders and has previously been reported to be indispensable for ionotropic glutamatergic neurotransmission in the hippocampus.
Christian Staehr, Hande Login, Elizaveta V. Melnikova, Magdalena Bakun, Ewelina Ziemlinska, Lilian Kisiswa, Simin Berenji Ardestani, Stella Solveig Nolte, Hans Christian Beck, Line Mathilde Brostrup Hansen, Dmitry Postnov, Alexei Verkhratsky, Anna R. Malik, Anders Nykjaer, Vladimir V. Matchkov   +14 more
wiley   +1 more source

Nonselective Endothelin Receptor Antagonist Initiated Soon After the Onset of Myocardial Infarction May Deteriorate 24-Hour Survival

, 2001
Chikako Takahashi, Yutaka Kagaya, Shigeto Namiuchi, Morihiko Takeda, Mitsumasa Fukuchi, Hiroki Otani, Mototsugu Ninomiya, Yuriko Yamane, Masahiro Kohzuki, Jun Watanabe, Kunio Shirato   +10 more
openalex   +1 more source

Engineered pulmonary artery tissues for measuring contractility, drug testing and disease modelling

British Journal of Pharmacology, Volume 182, Issue 12, Page 2585-2602, June 2025.
Abstract Background and Purpose Vasoreactivity of pulmonary arteries regulates blood flow through the lungs. Excessive constriction of these vessels contributes to pulmonary arterial hypertension (PAH), a progressive and incurable condition, resulting in right heart failure.
Adam L. Fellows, Kate Quigley, Venus Leung, Alexander J. Ainscough, Martin R. Wilkins, Harry Barnett, David Miller, Manuel Mayr, Beata Wojciak‐Stothard   +8 more
wiley   +1 more source

The safety of endothelin receptor antagonists in the treatment of pulmonary arterial hypertension: Protocol for a systemic review and network meta-analysis. [PDF]

Medicine (Baltimore), 2018
Gu ZC, Zhang YJ, Pan MM, Zhang C, Liu XY, Wei AH, Su YJ.   +6 more
europepmc   +1 more source

Obesity‐related glomerulopathy: How it happens and future perspectives

Diabetic Medicine, Volume 42, Issue 6, June 2025.
Abstract Obesity‐related glomerulopathy (ORG) is an emerging complication of excess adiposity. Its incidence rises alongside the obesity pandemic. Up to 40% of individuals can be affected by ORG, irrespective of the status of glomerular filtration rate and albuminuria.
Jian‐Wen Samuel Lee‐Boey, Jia‐Kai Tan, Zhan‐Foong Lim, Francesco Zaccardi, Kamlesh Khunti, Majid Ezzati, Edward W. Gregg, Lee‐Ling Lim   +7 more
wiley   +1 more source

Use of adjunctive glycaemic agents with vascular protective properties in individuals with type 1 diabetes: Potential benefits and risks

Diabetes, Obesity and Metabolism, Volume 27, Issue 6, Page 2920-2939, June 2025.
Abstract Glycaemic therapy in type 1 diabetes (T1D) is focused on insulin, with the majority of studies investigating different insulin preparations, delivery devices and dosing accuracy methods. While insulin deficiency is the key mechanism for hyperglycaemia in T1D, individuals with this condition can also develop insulin resistance (IR), making ...
Ahmad M. Rajab, Sam Pearson, Ramzi A. Ajjan   +2 more
wiley   +1 more source

Endothelin receptor antagonists in sickle cell disease: A promising new therapeutic approach. [PDF]

Life Sci, 2016
Fox BM, Kasztan M.
europepmc   +1 more source