Results 111 to 120 of about 313,061 (314)

Endothelial dysfunction in clinical practice: the role of laser Doppler flowmetry (literature review)

Mìžnarodnij Endokrinologìčnij Žurnal, 2019
This literature review deals with endothelial dysfunction. Endothelial dysfunction is presented in noninfectious di­seases of the 21st century and at the same moment is a predictor of cardiovascular and cerebrovascular diseases, especially in patients ...
О.B. Dynnyk, N.A. Marunchyn, S.Ye. Mostovy   +2 more
doaj   +1 more source

Changes in corneal endothelium cell characteristics after cataract surgery with and without use of viscoelastic substances during intraocular lens implantation

, 2015
Stephan D Schulze,1 Thomas Bertelmann,1 Irena Manojlovic,2 Stefan Bodanowitz,2 Sebastian Irle,3 Walter Sekundo11Department of Ophthalmology, Philipps University of Marburg, Marburg, 2Private Practice and Ambulatory Surgical Center, Bremen, 3Freelance ...
Sekundo W, Bertelmann T, Manojlovic I, Schulze SD, Bodanowitz S, Irle S   +5 more
core  

Vascular endothelium: Vasoactive mediators

, 1996
In most blood vessels, the endothelium generates both vasodilator and growth-stabilizing mediators under normal physiological circumstances. The vasodilator influence of the endothelium modulates the vasoconstriction induced by adrenergic nerves, blood ...
Vanhoutte, PM, Mombouli, JV
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Sex differences in endothelium-dependent vasodilator signals (NO and EDH) in the progression of vascular disease

, 2019
Female appears to have a lower risk of developing vascular diseases compared to age-matched male, until after menopause. Vascular diseases, in particular atherosclerosis, develop with aging, hypertension and hyperlipidemia, and are associated with an ...
Leung, SWS
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Apolipoprotein E-deletion potentiates endothelium-dependent relaxations to prostacyclin receptor activation in the mouse aorta

, 2019
Introduction: Nitric oxide (NO)-mediated relaxations of isolated arteries are blunted by ageing and high-fat diet, as well as by apolipoprotein E-deletion. Aims: The present study was designed to examine the prostacyclin receptor (IP)-mediated responses
Cheng, Y, Leung, SWS, Vanhoutte, PMGR, Dusting, GJ   +3 more
core  

Endothelium, endocardium, and cardiac contraction

, 1992
t is now recognised that vascular endothelium plays Im any functional roles including that of modulating vascular smooth muscle tone through the release of vasoactive agents such as endothelium derived relaxing factor (EDRF).’-’ The heart ...
Shah, Ajay M., Lewis, Malcolm John, Henderson, Andrew H., Warden-Smith, Jeremy   +3 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Endothelium-dependent NO-mediated vasodilation in humans is attenuated by peripheral a1-adrenoceptor activation

, 2005
Adriaan M Kamper, Anton JM de Craen, Rudi GJ Westendorp, Gerard J BlauwDepartments of Gerontology & Geriatrics, Leiden University Medical Center, Leiden, The NetherlandsObjectives: The release of nitric oxide is controlled by cholinergic and ...
Gerard J Blauw, Rudi GJ Westendorp, Anton JM de Craen, Adriaan M Kamper   +3 more
core