Results 271 to 280 of about 313,061 (314)
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Development of the Endothelium
2006Our understanding of the regulation of vascular development has exploded over the past decade. Prior to this time, our knowledge of vascular development was primarily based on classic descriptive studies. The identification of stem cells, lineage markers, specific growth factors and their receptors, and signalling pathways has facilitated a rapid ...
A M, Suburo, P A, D'Amore
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Hämostaseologie, 2015
SummaryThe endothelium is a widely distributed organ system that plays an important role in health and disease. The endothelium is remarkably heterogeneous in structure and function. One vital function of the endothelium is to maintain blood in its fluid state, and to provide controlled haemostasis at sites of vascular injury. In keeping with the theme
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SummaryThe endothelium is a widely distributed organ system that plays an important role in health and disease. The endothelium is remarkably heterogeneous in structure and function. One vital function of the endothelium is to maintain blood in its fluid state, and to provide controlled haemostasis at sites of vascular injury. In keeping with the theme
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British Journal of Dermatology, 2006
This article is a review of the role of the endothelium in psoriasis, with emphasis on angiogenesis and lymphocyte-endothelial ...
P M, Lowe +5 more
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This article is a review of the role of the endothelium in psoriasis, with emphasis on angiogenesis and lymphocyte-endothelial ...
P M, Lowe +5 more
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Endothelium and Allotransplantation
Transplantation, 2006Endothelial cells form the inner lining of blood vessels. The endothelium displays remarkable heterogeneity in structure and function. Phenotypic diversity reflects the ability of the endothelium to meet the demands of the underlying tissue. In addition to their critical role in homeostasis, endothelial cells are affected by, and contribute to, many ...
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2006
In recent decades, it has become evident that the endothelium is by no means a passive inner lining of blood vessels. This 'organ' with a large surface (approximately 350 m2) and a comparatively small total mass (approximately 110 g) is actively involved in vital functions of the cardiovascular system, including regulation of perfusion, fluid and ...
A R, Pries, W M, Kuebler
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In recent decades, it has become evident that the endothelium is by no means a passive inner lining of blood vessels. This 'organ' with a large surface (approximately 350 m2) and a comparatively small total mass (approximately 110 g) is actively involved in vital functions of the cardiovascular system, including regulation of perfusion, fluid and ...
A R, Pries, W M, Kuebler
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Experimental Gerontology, 2004
One link between aging and endothelial function is the inflammatory response. On one hand, the latter shortens the biological engaged by activated leukocytes against invaders or stressing agents. On the other hand, the surveyed tissues become targets of the toxicity of reactive oxygen species, ROS.
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One link between aging and endothelial function is the inflammatory response. On one hand, the latter shortens the biological engaged by activated leukocytes against invaders or stressing agents. On the other hand, the surveyed tissues become targets of the toxicity of reactive oxygen species, ROS.
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Restoring the Dysfunctional Endothelium
Current Pharmaceutical Design, 2007Nowadays the endothelium is considered a key determinant of vascular health. NO is the principal mediator of all endothelial protective effects, due to its antiinflammatory, antiproliferative, immunomodulatory and vasorelaxant properties. On the contrary, a growing body of evidence suggests that endothelial dysfunction is associated with cardiovascular
Elena Osto +3 more
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The endothelium in atherogenesis
Lupus, 2000The focus of this article is an overview of the endothelial changes that initiate and perpetuate the process of atherogenesis. The endothelium can undergo a series of changes which allow it to participate in the inflammatory response; this is known as endothelial cell activation (ECA).
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Vascular Grafts and the Endothelium
Endothelium, 2006This article discusses the importance of the endothelium for successful vascular grafts derived from both native arteries and synthetic materials. It also discusses the fundamental strategies to endothelialize synthetic grafts in animal experiments and in the clinic, as well as the use of endothelial progenitor cells (EPCs), bone marrow-derived cells ...
Hoenig, Michel R. +2 more
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ANTIPHOSPHOLIPID ANTIBODIES AND THE ENDOTHELIUM
Rheumatic Disease Clinics of North America, 2001The interaction between aPL (particularly anti-beta 2GPI antibodies) and endothelium does represent a potential pathogenetic mechanism for the thrombotic manifestations of the syndrome. The autoantibody-mediated EC activation probably plays a role in sustaining the appearance of a proadhesive, proinflammatory, and procoagulant phenotype.
P. L. Meroni +4 more
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