Indoor allergens and endotoxins in relation to cockroach infestations in low-income urban homes. [PDF]
Kakumanu ML +4 more
europepmc +1 more source
An intronless version of the white pupae (wp) gene was engineered to restore the wild type brown puparium color in white pupae phenotype mutants of the Mediterranean fruit fly, Ceratitis capitata. Functionality of the minimal gene version (mini‐wp) was verified in vivo, as one copy of mini‐wp successfully restored the wild type phenotype in homozygous ...
Lucas Henrique Figueiredo Prates +4 more
wiley +1 more source
Joint association of indoor allergens, endotoxins, heavy metals, and parabens with allergy-related outcomes in U. S. adults. [PDF]
Xue M, Wei X, Zhang Y, Ma X.
europepmc +1 more source
Cellular Stress, Inflammation and Barrier Damage in Gut Epithelial Cells Caused by Aspartame
This study shows that aspartame, at dietary‐relevant doses, induces cytotoxicity, cellular distress associated with endoplasmic reticulum stress, oxidative stress, DNA replication and repair mechanism disturbance culminating in epithelial barrier damage.
Yagiz Pat +16 more
wiley +1 more source
TIR-domain-containing protein C as modulator of innate immune checkpoints. [PDF]
Heine L +9 more
europepmc +1 more source
The Therapeutic Potential of Farm Dust Extracts in a Mouse Model of Eosinophilic Inflammation
Farm dust extract (FDE) treatment reduces airway eosinophilia, mucus overproduction, and MHC‐II expression on DCs, limiting antigen presentation and Th2 inflammation. It increases PD‐L1 on DCs, promoting T cell deactivation. Additionally, FDE enhances Tregs and upregulates CTLA‐4, reinforcing suppression.
Rabia Ülkü Korkmaz +16 more
wiley +1 more source
Structure Elucidation, Biological and Molecular Docking Studies of the δ‑Endotoxin Cry1Ca17 from <i>Bacillus thuringiensis</i> Strain BUPM14. [PDF]
Driss F +5 more
europepmc +1 more source
Oral Immunotherapy Induces Shift in lncRNA Expression Modulating Allergen‐Specific Immune Responses
We used PBMC transcriptome from 50 hen's egg‐allergic patients to study the role of lncRNA in OIT. Positive correlation was found between 17 lncRNAs and the IL‐4/IL‐13 pathway in vivo, and the expression of the selected lncRNA aligned with CXCL8 upon PBMC egg‐restimulation.
Olivia Liong +5 more
wiley +1 more source
SARS-CoV-2 Nucleocapsid Protein Does Not Induce Inflammation in Endothelial Cells or Monocytes. [PDF]
Tufail M +4 more
europepmc +1 more source
Exposures in Indoor Air Affecting Health
ABSTRACT Indoor air quality (IAQ) is influenced by a wide range of chemical, biological and physical agents that can negatively impact physical, immunological and mental health. Adverse health effects depend on the type and concentration of pollutants, duration of exposure, and individual susceptibility.
Maria Hartiala +38 more
wiley +1 more source

