Results 51 to 60 of about 223,059 (285)

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng, Camila B. Tovani, Simona Bianco, Gianni Comandini, Aya Elghajiji, Mina Aleemardani, Roxana Moscalu, Jeremie Zappia, Bianca Fernandes, Olivia Annett, Chrissy L. Hammond, Jason Wong, Dave J. Adams, Fabrizio Scarpa, Michael R. Whitehouse, Annela M. Seddon, James P. K. Armstrong   +16 more
wiley   +1 more source

Antimicrobial Efficacy of a Taurolidine‐Based Antimicrobial Compound on Contaminated Surfaces Simulated in a Standardized 4‐Field Test

Advanced Healthcare Materials, EarlyView.
As implantable medical devices become indispensable to modern medicine, a silent threat grows alongside them: device‐associated infections. Despite decades of antibiotic innovation, infection rates keep climbing, costing lives and billions in healthcare expenses.
Benito Baldauf, Hendrik Bonnemeier, Ernest W. Lau, Jana Hummel, Reinhard Vonthein, Ojan Assadian   +5 more
wiley   +1 more source

SiO2‐CaOCME/Poly(Tetrahydrofuran)/Poly(Caprolactone) 3D‐Printed Scaffolds Drive Human‐Bone Marrow Stromal Cell Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
3D printed hybrid scaffolds combining bioactive silica–calcium chemistry with elastic polymers guide human bone stem cells to form bone. The scaffolds support cell survival, organization, and invasion while releasing osteogenic ions. Together, architecture and composition drive bone‐specific gene expression, extracellular matrix organization, and ...
David R. Sory, Agathe C.M. Heyraud, Julian R. Jones, Sara M. Rankin   +3 more
wiley   +1 more source

Cationic Polystyrene Resolves Nonalcoholic Steatohepatitis, Obesity, and Metabolic Disorders by Promoting Eubiosis of Gut Microbiota and Decreasing Endotoxemia. [PDF]

, 2017
A pandemic of metabolic diseases, consisting of type 2 diabetes, nonalcoholic fatty liver disease, and obesity, has imposed critical challenges for societies worldwide, prompting investigation of underlying mechanisms and exploration of low-cost and ...
Bai, Li, Chen, Jingjing, Chen, Zishou, Duan, Yixiang, Duan, Zhongping, Han, Yuan-Ping, Hu, Richard, Ju, Zhongyuan, Li, Wenwen, Li, Yan, Liu, Yong, Luo, Mei, Pandol, Stephen J, Su, Danmei, Sun, Qun, Wu, Pengfei, Xiao, Zhixiong, Zeng, Yilan, Zhang, Li, Zhang, Xiaohui, Zheng, Han, Zheng, Sujun, Zhu, Airu   +22 more
core   +1 more source

Evaluating Cytocompatibility of Corynebacterium glutamicum‐poly Vinyl Alcohol Living Biomaterials for Ocular Use

Advanced Healthcare Materials, EarlyView.
In ophthalmology, living biomaterials such as living contact lenses appear promising for sustained drug delivery or biosensing. The cytocompatibility of Cg‐PVA hydrogels, developed as a model living contact lens, is investigated with the ocular surface, showing their potential translation to the clinic.
Krupansh Desai, Lorely Garcia‐Sanchez, Maryam Amini, Lara Luana Teruel‐Enrico, Silke Siegrist, Aránzazu del Campo, Sara Trujillo   +6 more
wiley   +1 more source

Unique genome-wide transcriptome profiles of chicken macrophages exposed to Salmonella-derived endotoxin

BMC Genomics, 2010
Background Macrophages play essential roles in both innate and adaptive immune responses. Bacteria require endotoxin, a complex lipopolysaccharide, for outer membrane permeability and the host interprets endotoxin as a signal to initiate an innate immune
Nettleton Dan, Wannemuehler Michael J, Tuggle Christopher K, Ciraci Ceren, Lamont Susan J   +4 more
doaj   +1 more source

Amine‐Functionalized Chitosan/dECM Composite Promotes Cutaneous Regeneration and Hair Follicle Activation by Regulating Oxidative Stress and Inflammation

Advanced Healthcare Materials, EarlyView.
An amine‐functionalized chitosan and hydrolyzed dECM composite promotes cutaneous regeneration by modulating oxidative stress and inflammatory pathways. The material accelerates wound closure and stimulates hair follicle activation in UV‐damaged cutaneous tissue.
Yu‐Jin Kim, Seokheon Hong, Jae Hwi Lee, Jongmin Lee, Jae Jun Kang, Jiseon Bae, Jino Kim, Dong‐Hwee Kim, Jin Yoo, Mi Sun Cha, Su Hee Kim, Youngmee Jung   +11 more
wiley   +1 more source

Sex Differences in the Effect of Inflammation on Subjective Social Status: A Randomized Controlled Trial of Endotoxin in Healthy Young Adults. [PDF]

, 2019
It has been established that inflammation leads to a variety of changes in social experience, but one area of social experience that has been overlooked is subjective social status.
Breen, Elizabeth C, Eisenberger, Naomi I, Irwin, Michael R, Jevtic, Ivana, Moieni, Mona, Muscatell, Keely A   +5 more
core  

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Endotoxin Removal from Water Using Heterogenus Catalytic Ozonation by Bone Char [PDF]

آب و فاضلاب, 2011
The endotoxin is one of pollutants with lipopolysaccharide structure which release from gram negative bacteria and cyanobacters. The aim of this study was removal of endotoxin from water using catalytic ozonation by bone char.
Abas Rezaee, Ghader Ghanizadeh, Ahmadreza Yazdanbakhsh, Ghorban Behzadian Nejad   +3 more
doaj