Results 71 to 80 of about 214,836 (286)

Endotoxin induces fibrosis in vascular endothelial cells through a mechanism dependent on transient receptor protein melastatin 7 activity.

PLoS ONE, 2014
The pathogenesis of systemic inflammatory diseases, including endotoxemia-derived sepsis syndrome, is characterized by endothelial dysfunction. It has been demonstrated that the endotoxin lipopolysaccharide (LPS) induces the conversion of endothelial ...
Cesar Echeverría, Ignacio Montorfano, Tamara Hermosilla, Ricardo Armisén, Luis A Velásquez, Claudio Cabello-Verrugio, Diego Varela, Felipe Simon   +7 more
doaj   +1 more source

Potential causes of mortality for horseshoe crabs (Limulus polyphemus) during the biomedical bleeding process [PDF]

, 2006
Biomedical companies catch and bleed horseshoe crabs for the production of Limulus amebocyte lysate (LAL), a product used for protecting public health (Berkson and Shuster, 1999).
Berkson, Jim, Hurton, Lenka
core  

Effect of pentoxifylline on diaphragmatic contractility in septic rats. [PDF]

, 2008
We investigated the effects of pentoxifylline (PTX) on endotoxin-induced diaphragmatic dysfunction in vitro. Seventy-two rats were divided into 3 groups: a group in which endotoxin (20 mg/kg) was injected intraperitoneally (endotoxin-group), a group in ...
Danjo, Wataru, Fujimura, Naoyuki, Ujike, Yoshihito   +2 more
core   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

Effects of endotoxin exposure on childhood asthma risk are modified by a genetic polymorphism in ACAA1

BMC Medical Genetics, 2011
Background Polymorphisms in the endotoxin-mediated TLR4 pathway genes have been associated with asthma and atopy. We aimed to examine how genetic polymorphisms in innate immunity pathways interact with endotoxin to influence asthma risk in children ...
Sordillo Joanne E, Sharma Sunita, Poon Audrey, Lasky-Su Jessica, Belanger Kathleen, Milton Donald K, Bracken Michael B, Triche Elizabeth W, Leaderer Brian P, Gold Diane R, Litonjua Augusto A   +10 more
doaj   +1 more source

Correlation between levels of airborne endotoxin and heavy metals in subway environments in South Korea

Scientific Reports, 2021
This study aimed to evaluate the exposure levels and variation in airborne endotoxin and heavy metals such as aluminum, chromium (Cr), iron (Fe), manganese (Mn), nickel (Ni), zinc, and lead (Pb) in the three different South Korean subway environments ...
Sungho Hwang, So-Yeon Kim, Sangjun Choi, Sangwon Lee, Dong-Uk Park   +4 more
doaj   +1 more source

Eicosapentaenoic acid preserves diaphragm force generation following endotoxin administration [PDF]

, 2010
INTRODUCTION: Infections produce severe respiratory muscle weakness, which contributes to the development of respiratory failure. An effective, safe therapy to prevent respiratory muscle dysfunction in infected patients has not been defined.
Gerald S Supinski, Jonas Vanags, Leigh Callahan   +2 more
core   +2 more sources

Investigating bacteriophages targeting the opportunistic pathogen Acinetobacter baumannii [PDF]

, 2020
The multi-drug resistance of the opportunistic pathogen Acinetobacter baumannii is of growing concern, with many clinical isolates proving to be resistant to last resort as well as front line antibiotic treatments.
Christie, Gabrielle S., Dowson, Christopher G., Leungtongkam, Udomluk, Millard, Andrew D., Moat, John, Sagona, Antonia P., Sitthisak, Sutthirat, Smith, Sophie, Styles, Kathryn, Thummeepak, Rapee, Wellington, Elizabeth M. H.   +10 more
core   +1 more source

Redefining Dendritic Cell Vaccines: Synergistically Co‐priming DC and B Cells With Nanoparticles Loading Whole Cell Antigens Maximizes the Efficacy of DC Vaccines

Advanced Science, EarlyView.
Dendritic cells (DC) vaccine is an important type of vaccines. However, the limited efficacy of DC vaccines hinders their widely application. This study redefines DC vaccines and provides a new DC‐BC vaccine that have much better therapeutic efficacy.
Xiangxiang Xu, Xianlan Chen, Jin Wang, Yuhan Liu, Sidra Mustafa, Lu Diao, Rongrong Zhao, Haiyang Chi, Kang Hu, Jiashan Zhu, Jun Zhao, Mi Liu   +11 more
wiley   +1 more source

Endotoxins in Household Dust in Northern China: Associations with Home Environment Factors and Childhood Asthma and Allergies

Atmosphere
The available information on endotoxin in Chinese households is limited and there is inconsistency regarding its impact on asthma and allergies in children. A case-control study was performed in 324 homes in Tianjin, China. Linear regression analysis was
Yuxuan Zhao, Yixin Liu, Lianwang Cui, Jing Hou, Feng Gao, Dan Norback, Yuexia Sun   +6 more
doaj   +1 more source