Results 131 to 140 of about 2,607 (169)

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source

Long‐Term Outcomes of Omniflow II and BioIntegral Xenografts for Open Aortic Reconstruction in Predominantly Infected Settings: A Multicenter Cohort Study

World Journal of Surgery, EarlyView.
Evidence surrounding conduit selection for open in situ aortic reconstruction remains limited, particularly for xenograft use in infected settings. We evaluated long‐term outcomes after open aortic and aorto‐iliac reconstruction using BioIntegral No‐React bovine grafts and Omniflow II biosynthetic grafts in patients unsuitable for autologous vein ...
Tijmen W. Kraai, Eline I. Reinders Folmer, Barzi Gareb, David J. Liesker, Ben R. Saleem, Clark J. Zeebregts, Vascular Xenograft Research Group   +6 more
wiley   +1 more source

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source

Clinical Vignette: Piperacillin/tazobactam‐associated myoclonic status epilepticus in a patient with end‐stage renal failure on hemodialysis

Epileptic Disorders, EarlyView.
O. M. Malanga, G. Giovannelli, G. Pastorelli, S. Fittante, A. Poggesi, E. Rosati   +5 more
wiley   +1 more source

Contrast‐Induced Encephalopathy Following Elective Endovascular Aneurysm Treatment: The Role of Dual‐Energy CT and Correlation With Delphi Diagnostic Criteria

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction Contrast‐induced encephalopathy (CIE) is an increasingly recognised neurological complication of iodinated contrast administration during neurointerventional procedures. Recently published 2025 Delphi‐based diagnostic criteria and management algorithms aim to standardise clinical practice; however, optimal neuroimaging strategies ...
Kaiwen Cabbabe, Charles Li, Shuangyue Tan, Lisa Broadley, Gerard S. Goh, Cameron Williams, Conor Houlihan, Helen Kavnoudias, Steve Bush, Carlos Chung, Winston Chong   +10 more
wiley   +1 more source

Ethnic Differences in Outcomes of Endovascular Thrombectomy in New Zealand

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction Stroke is a leading cause of morbidity and mortality in New Zealand, with ethnic disparities known to exist. Endovascular thrombectomy (EVT) has proven efficacy in reducing or preventing disability for stroke patients, but little is known about ethnic differences in functional outcomes following EVT in New Zealand.
Jaron Huang, Alicia Tyson, Muthu Muthappan, Annemarei Ranta   +3 more
wiley   +1 more source

Micro‐Nanoplastics Significantly Increase Adverse Events and Economic Burden Associated With Carotid Endarterectomy: A Health Economic Modelling Evaluation

ANZ Journal of Surgery, EarlyView.
Current research reports that micro‐nanoplastics may increase the burden of cardiovascular disease with significant human and economic consequences. The detection of plastic particles in biological matrices is challenging and rigorous research is required to investigate the clinical and broader public health implications of microplastics.
Adrian Goldsworthy, Marcus Randall, Oystein Tronstad, Jacky Suen, John F. Fraser   +4 more
wiley   +1 more source

Pulmonary Embolism—A Century of Progress

ANZ Journal of Surgery, EarlyView.
Reviews a century of progress in the diagnosis, prevention, and management of pulmonary embolism; from the first successful surgical embolectomy in 1924 to advanced imaging, pharmacological thromboprophylaxis, and treatment. In the 21st century, advances include catheter‐directed thrombolysis or mechanical thrombectomy under decision‐making guidance of
D. A. Watters
wiley   +1 more source

Long‐Term Outcomes After Elective Splenectomy for Haematological Disease: A 27‐Year Single‐Centre Study

ANZ Journal of Surgery, EarlyView.
Splenectomy is a safe and effective treatment option in selected patients with haematological disease, despite declining referrals over the last 27 years in the era of targeted therapies. Outcomes are favourable when performed laparoscopically and long‐term follow‐up demonstrates sustained haematologic benefit in surviving patients.
Salil Dutt Barrett, Anthony Downhill, Douglas Greer, William Stevenson, Ian Kerridge, Chris Ward, Matthew Greenwood, Naomi Mackinlay, Luke Coyle, Thomas J. Hugh   +9 more
wiley   +1 more source

Geometry‐Related Technical Complications After LVAD Implantation: Impact on Device Dysfunction and Clinical Outcomes

Artificial Organs, EarlyView.
Preventable geometric failure modes, such as outflow graft kinking and inflow malposition, frequently cause HeartMate 3 dysfunction. This study identifies these complications as key drivers of device‐related morbidity, highlighting the importance of optimized surgical positioning to ensure long‐term device performance and improved clinical outcomes ...
Ali Saad Merzah, Ezin Deniz, Sara Knigge, Jasmin Hanke, Alina Zubarevich, Mohamad Dia, Chaikovska Sofia, Todurov Borys, Saeed Torabi, Bastian Schmack, Alexander Weymann, Zurab Darbaidze, Josephina Haunschild, Christian D. Etz, Max Biewer, Arjang Ruhparwar, Jan D. Schmitto, Günes Dogan   +17 more
wiley   +1 more source