Results 101 to 110 of about 168,138 (329)

DNase1 RS1053874 Polymorphism is Associated with Early Neurological Recovery through NET Modulation and with Long‐Term Survival in Ischemic Stroke: A Prospective Cohort Study

Annals of Neurology, EarlyView.
Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito, P. Calleja, L. Alzamora, A. Ruiz‐García, A. Martínez‐Salio, M. Muñoz‐García, F. Ostos, A. García‐Culebras, A. Moraga, M.A. Moro, I. Lizasoain   +10 more
wiley   +1 more source

Efficacy and safety of endovascular thrombectomy in mild ischemic stroke: results from a retrospective study and meta-analysis of previous trials

BMC Neurology, 2019
Background Mechanical thrombectomy has been proven as a standard care for moderate to severe ischemic stroke with anterior large vessel occlusion (LVO); however, whether it is equally effective in mild ischemic stroke (MIS) is controversial.
Xian-Jin Shang, Zhong-Hua Shi, Cai-Feng He, Shuai Zhang, Yong-Jie Bai, Yong-Tao Guo, Bo Sun, Shun Li, Huai-Ming Wang, Zhi-Ming Zhou, Wen-Jie Zi, Xin-Feng Liu   +11 more
doaj   +1 more source

Does Malignancy Status Effect Outcomes in Patients With Large Vessel Occlusion Stroke and Cancer Who Underwent Endovascular Thrombectomy?

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Cancer is associated with an increased risk of acute ischemic stroke, including large vessel occlusions. Whether cancer status affects outcomes in patients with large vessel occlusions that undergo endovascular thrombectomy remains unknown ...
Fatma Shalabi, Tzvika Sacagiu, Asaf Honig, Jeremy Molad, Zeev Itsekson‐Hayosh, Hen Hallevi, David Orion, Shorooq Aladin, John M. Gomori, Jose E. Cohen, Ronen R. Leker   +10 more
doaj   +1 more source

Perfluorocarbon Enhanced Glasgow Oxygen Level Dependent (GOLD) magnetic resonance metabolic imaging identifies the penumbra following acute ischemic stroke [PDF]

, 2018
The ability to identify metabolically active and potentially salvageable ischaemic penumbra is crucial for improving treatment decisions in acute stroke patients.
Brennan, David, Deuchar, Graeme A., Holmes, William M., Macrae, I. Mhairi, Santosh, Celestine, Shaw, Martin   +5 more
core   +1 more source

Endovascular Thrombectomy for Large Ischemic Strokes with ASPECTS 0–2: a Meta-analysis of Randomized Controlled Trials

Clinical Neuroradiology
Randomized controlled trials (RCTs) demonstrated a treatment effect of endovascular thrombectomy in acute ischemic stroke with large infarct, commonly defined as an Alberta Stroke Program Early CT Score (ASPECTS) of 3–5.
L. Winkelmeier, M. Maros, F. Flottmann, C. Heitkamp, G. Schön, G. Thomalla, J. Fiehler, U. Hanning   +7 more
semanticscholar   +1 more source

Role of Intravenous Thrombolytics Prior to Endovascular Thrombectomy

Stroke, 2022
Intravenous thrombolytics and endovascular thrombectomy for ischemic stroke have evolved in parallel. However, the best approach to combine these reperfusion therapies in patients eligible for both strategies remains uncertain.
B. Campbell, M. Kappelhof, U. Fischer
semanticscholar   +1 more source

Individualized Treatment in Distal and Medium Vessel Occlusion Stroke Using a Validated Explainable Counterfactual Treatment Estimation Model

Annals of Neurology, EarlyView.
Objective The optimal treatment for distal medium vessel occlusion (DMVO) stroke remains uncertain, and evidence comparing endovascular therapy (EVT) with medical management (MM) is limited. We aimed to develop and validate a predictive modeling tool to assess individual treatment benefit in DMVO stroke using explainable counterfactual treatment ...
Mohamed F. Doheim, Mahmoud H. Mohammaden, Hend Abdelhamid, Marta Olive‐Gadea, Marc Rodrigo‐Gisbert, Manuel Requena, Johanna T. Fifi, James E. Siegler, Santiago Ortega‐Gutierrez, Mohamad Abdalkader, Ali Alaraj, Wei Hu, Thanh N. Nguyen, Diogo C. Haussen, Raul G. Nogueira   +14 more
wiley   +1 more source

Endovascular thrombectomy for the treatment of large ischemic stroke: a systematic review and meta-analysis of randomized control trials [PDF]

, 2023
Travis J. Atchley, Dagoberto Estévez-Ordoñez, Nicholas M. B. Laskay, Borna E. Tabibian, Mark R. Harrigan   +4 more
openalex   +1 more source

Radiation outcome in mechanical thrombectomy of acute ischemic stroke

Translational Neuroscience, 2019
Mechanical thrombectomy is recommended for acute ischemic stroke (AIS) with large artery occlusion. Radiation during the endovascular procedure would increase the risk of skin diseases.
Cai Xiaoying, Ding Xianhui, Wang Wenbin, Yang Ke, Zhou Zhiming, Fang Yannan, Shi XiaoLei   +6 more
doaj   +1 more source

Alberta Stroke Program Early CT Score applied to CT angiography source images is a strong predictor of futile recanalization in acute ischemic stroke [PDF]

, 2016
The final publication is available at Springer via http://dx.doi.org/10.1007/s00234-016-1652-7Introduction Reliable predictors of poor clinical outcome despite successful revascularization might help select patients with acute ischemic stroke for ...
Alonso de Leciñana, María, Calleja, Patricia, Díaz-Otero, Fernando, Díez-Tejedor, Exuperio, Fandiño, Eduardo, Fuentes, Blanca, García-Pastor, Andrés, Kawiorski, Michal M., Lourido, Daniel, Martínez-Sánchez, Patricia, Marín, Begoña, Ruiz-Ares, Gerardo, Sanz-Cuesta, Borja E., Sierra-Hidalgo, Fernando, Vicente, Agustina   +14 more
core   +2 more sources