Results 71 to 80 of about 9,456,030 (287)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The Psychological Correlates of Endowment Effect: Individualism-Collectivism, Perspective Taking, and Real and Hypothetical Endowment Effects [PDF]
, 2002 In this study conducted in Boğaziçi University with 121 participants, the psychological correlates of the endowment effect are probed. The endowment effect is the asymmetry between the amount that a given individual would like to pay for a certain good ...
Gezgin, Dr. Ulas Basar
core
Gender wage differences in the selected Czech public sector company
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2012 The issue of wage disparity between men and women belongs to the current and widely discussed topics. The attention given to this subject also reflects the fact that the issue of the equality between women and men and non-discrimination by gender is ...
Veronika Hedija, Petr Musil
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Endowment effect theory and the Samuelson solution – a thought experiment [PDF]
Thaler (1980) employs prospect theory to explain the endowment effect, i.e. the empirically observed disparity between the willingness to pay for a certain good (WTP) and the willingness to accept retribution payments in exchange for giving up this good (
Bischoff, Ivo
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The Endowment Effect in Groups with and without Strategic Incentives [PDF]
The realization of market transactions often depends on decisions in groups in which members are anonymous and cannot communicate, but have interrelated outcomes.
Stephan Tontrup +3 more
core
WTP vs.WTA: Christmas Presents and the Endowment Effect [PDF]
Using data on the valuation of Christmas gifts received by students in different fields at a German university, we investigate whether the endowment effect differs between students of economics and other respondents and whether it varies with the market ...
Thomas K. Bauer, Christoph M. Schmidt
core +2 more sources
The Endowment Effect in a Public Good Experiment [PDF]
Previous tests of the endowment effect have usually observed WTA-WTP disparities. Here, a public good experiment is employed. Both account framing and duration framing treatments are introduced to alter subjects’ perceived control over an initial ...
W. Robert Nelson, Edward J. Lopez
core
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source