Results 71 to 80 of about 285,011 (291)
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
The Endowment Effect and Housing Studies: The Role of Multiple Reference Points
Critical Housing AnalysisOne of the most researched and proven behavioural biases is the endowment effect, which manifests in people's higher valuation of goods they own relative to goods they do not.
Mateusz Tomal
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Real estate brokerage and endowment effects in the housing market: Evidence from Poland
International Journal of Strategic Property ManagementIn the housing market, the prices sellers would be willing to accept to sell their properties exceed the prices buyers would be willing to pay for them.
Mateusz Tomal
doaj +1 more source
Jurisprudential and Legal Analysis of the Terminator’s Condition in Contract of the Endowment [PDF]
آموزههای فقه مدني, 2019 There is no specific comment in jurisprudence regarding the validity or voidness of the endowment that is conditioned by the terminator, but the jurists have provided different opinions about veracity and invalidity endowment contract and entailment in ...
Seyyed Mahdi Quraishi +2 more
doaj
Gender wage differences in the selected Czech public sector company
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2012 The issue of wage disparity between men and women belongs to the current and widely discussed topics. The attention given to this subject also reflects the fact that the issue of the equality between women and men and non-discrimination by gender is ...
Veronika Hedija, Petr Musil
doaj +1 more source
The Endowment Effect in Groups with and without Strategic Incentives [PDF]
The realization of market transactions often depends on decisions in groups in which members are anonymous and cannot communicate, but have interrelated outcomes.
Andreas Glöckner +3 more
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Learning to Like What You Have - Explaining the Endowment Effect [PDF]
The endowment effect describes the fact that people demand much more to give up an object than they are willing to spend to acquire it. The existence of this effect has been documented in numerous experiments. We attempt to explain this effect by showing
Georg Kirchsteiger +2 more
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