Results 131 to 140 of about 1,860,209 (301)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Spectrophotometric determination of fe(iii) with tiron in the presence of cationic surfactant and its application for the determination of iron in al-alloys and cu-based alloys

, 1994
A sensitive spectrophotometric method for the determination of iron with tiron and a cationic surfactant, cetylpyridinium chloride, at pH 5.6 is reported.
Tiwari, M, Bhadani, S N, Agrawal, A, Kavipurapu, C S   +3 more
core   +1 more source

Quantitation Methods of Thermopsis Alkaloids: A Review

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. The major alkaloids of Thermopsis lanceolata R. Br. herb are thermopsine (N-methylcytisine), pachycarpine, and anagyrine, while the seeds predominantly contain cytisine used to treat tobacco addiction. Differing toxicity and pharmacological
N. P. Antonova, S. D. Kakhramanova, S. D. Alidzhanova, S. S. Prokhvatilova, E. P. Shefer   +4 more
doaj   +1 more source

Citation.js: Endpoint on RunKit

, 2017
Citation.js: Endpoint on RunKit A while back I tweeted about making a simple Citation.js API Endpoint with RunKit.
Lars Willighagen
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

A Result on Output Feedback Linear Quadratic Control [PDF]

In this note we consider the static output feedback linear quadratic control problem.We present both necessary and sufficient conditions under which this problem has a solution in case the involved cost depend only on the output and control variables ...
Weeren, A.J.T.M., Engwerda, J.C.
core  

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Iran's Role and Power in the Region and the International System

, 2009
The report contains a series of recommendations related to Iran, specifically in the areas of Iran's relations in its region, Iran's nuclear program and multilateral nuclear diplomacy, and Iran's relations with the EU and the US.
Liechtenstein Institute on Self-Determination
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source