Results 231 to 240 of about 1,860,209 (301)

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Effects of Lactic Acid Bacteria Fermentation on the Physicochemical Properties, Nutritional Value, and Sensory Characteristics of a White Kidney Bean-Based Beverage. [PDF]

Foods
Xu Y, Sun L, Gu Y, Zhuang Y, Liang H, Ding Y, Fan X.   +6 more
europepmc   +1 more source

RBE as a function of neutron energy [PDF]

, 1976
Rossi, H. H., Teedla, P., Kellerer, Albrecht M., Hall, E. J.   +3 more
core  

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

Multi-Endpoint Prediction of Bioactivity and ADMET Properties Coupled with Multi-Objective Optimization in Molecular Descriptor Space for Candidate ERα Antagonists. [PDF]

Pharmaceuticals (Basel)
Cui Y, Qiao Y, Ren H, Qiu L.
europepmc   +1 more source

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source

Blinding and quality of life endpoints in randomised trials of stable angina: a meta-epidemiological study. [PDF]

Open Heart
Jelf D, Jelf M.
europepmc   +1 more source

Comparing diagnostic prostate cancer biomarkers using a framework of clinically meaningful criteria. [PDF]

BJUI Compass
Wang S, Nabavizadeh B, Ramaswamy A, Davuluri M, Zhang TR, Tzeng M, Feiertag N, Hu JC.   +7 more
europepmc   +1 more source

A Practical Guide to Implementing Real-World Evidence as Primary Basis for Approval and Label Expansion. [PDF]

Clin Pharmacol Ther
Mayne TJ, Brookhart MA, Dreyer NA.
europepmc   +1 more source

Leveraging AI to Evaluate Minimal Residual Disease Endpoint Surrogacy in Multiple Myeloma. [PDF]

Cancer Res Commun
Ren Z, Zhao Z, Cowan AJ, Ma W, Xie E, Shi Q.   +5 more
europepmc   +1 more source