Results 91 to 100 of about 214,690 (314)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Assessment of Perceived Effort Through On-Field Hydration Monitoring: A Case Analysis

Life
This case report examines the correlation between hydration, weight variation, and perceived effort in a 43-year-old amateur athlete during a self-supported 81.5 km crossing of Death Valley, completed over 3 days with significant elevation changes ...
Alexander Bertuccioli, Roberto Cannataro, Davide Sisti, Giordano Bruno Zonzini, Massimiliano Cazzaniga, Marco Cardinali, Francesco Di Pierro, Aurora Gregoretti, Nicola Zerbinati, Mariarosaria Matera, Ilaria Cavecchia, Chiara Maria Palazzi   +11 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Chapter 11: Self-talk and endurance performance [PDF]

, 2019
Athletes participating at all levels of endurance performance can relate to the impact of psychological factors. Whether it is motivation, self-belief, feeling nervous before a race, exercise-induced pain, sticking to a pacing strategy, or thoughts ...
McCormick, Alister, Hatzigeorgiadis, Antonis   +1 more
core  

Reverse periodization in ultratrail: The road to the 2023 World Mountain and Trail Running Championships of an elite female ultrarunner

Current Issues in Sport Science
Introduction and Purpose Traditionally, linear periodization has been widely applied to endurance training programs, whereas reverse periodization has been often used for shorter endurance events (Clemente-Suárez et al., 2015; Clemente-Suárez et al ...
Diego Jaén-Carrillo, Arcadi Margarit-Boscà   +1 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

The effects of eccentric arm crank training on upper body performance in elite athletes with a spinal cord injury

Current Issues in Sport Science
Introduction Eccentric strength training is a promising approach to improving upper body strength in athletes, as this type of training has several advantages over training that involves concentric or isometric muscle action (Hoppeler, 2016 ...
Fabian Ammann, Ann Knuchel, Anneke Hertig-Godeschalk, Claudio Perret   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The endurance athletes heart: acute stress and chronic adaptation

, 2012
The impact of endurance exercise training on the heart has received significant research and clinical attention for well over a century. Despite this, many issues remain controversial and clinical interpretation can be complex of biomarkers of ...
Gaze, D.C., Green, D.J., Somauroo, J., George, K., Whyte, G.P., Shave, R.E., Oxborough, D.   +6 more
core   +1 more source