Results 101 to 110 of about 214,690 (314)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

[News Clip: Endurance fliers]

open access: yes, 1958
Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about two endurance pilots who had been flying for over 1200 hours touching down in ...
WBAP-TV (Television station : Fort Worth, Tex.)
core  

Modulation of exercise-induced gene expression in human skeletal muscle by exercise intensity, training status and short-term endurance training [PDF]

open access: yes, 2008
A single bout of exercise generates a robust, but transient, increase in mRNA abundance for a multitude of genes, which is thought to contribute to the recovery from and adaptation to exercise.
Egan, Brendan
core  

Identifying Variations in Motor Fitness Components among Upper Primary and Secondary School Male Students

open access: yesPhysical Education Theory and Methodology
Background. Motor fitness helps students develop academically and socially. The students are more engaged in fitness activities with classmates of similar skills.
Jupender Singh Bhagi   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An evaluation of gastrocnemius muscle structure and function in endurance runners and low physical activity individuals

open access: yes, 2013
Includes abstract.Includes bibliographical references.Distance running has become increasingly popular in recreational runners. The gastrocnemius is the main muscle used for propulsion in running, and may be at risk for injury due to its morphology.
Buchholtz, Kim
core  

Meta-analyses of the effects of high-intensity interval training in elite athletes—part I: mean effects on various performance measures

open access: yesFrontiers in Physiology
IntroductionMeta-analysts have found that high-intensity interval training (HIIT) improves physical performance, but limited evidence exists regarding its effects on highly trained athletes, measures beyond maximum oxygen uptake (V˙O2max), and the ...
Hans-Peter Wiesinger   +11 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Aerobic Endurance Development in 13 and 14 Year-Old Swimmers

open access: yesBulletin of the Transilvania University of Braşov: Series IX Sciences of Human Kinetics
In the specialized literature, physical effort is considered a request of the body above the rest level, a stimulus applied in order to adapt. Sporting physical effort determines the modification of homeostasis, stabilizing it in a certain period of time,
C. Tartalranu, D. Ortanescu
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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