Results 121 to 130 of about 554,165 (297)

Endurance [PDF]

Anesthesiology, 2013
openaire   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

High‐level performances following low altitude training and tapering in warm environments in elite racewalkers

European Journal of Sport Science
Current guidelines for prolonged altitude exposure suggest altitude levels ranging from 2000 to 2500 m to optimize an increase in total hemoglobin mass (Hbmass). However, natural low altitude locations (
Bastien Krumm, Brent Vallance, Louise Burke, Johan Garcia, Janne Bouten, Franck Brocherie, Jonas J. Saugy, Francesco Botrè, Raphael Faiss   +8 more
doaj   +1 more source

The Comparison of Motoric Characteristics of Young Soccer Players According to Their Playing Positions [PDF]

Sportif Bakış Spor ve Eğitim Bilimleri Dergisi, 2016
The purpose of this study was to compare motoric features, 10-30m speed, agility, flexibility, standing long jump and yo-yo 1 test according to playing position at young soccer players.
Ayşegül Yapıcı, Eray Aydın, Eylem Çelik, Gizem Başkaya   +3 more
doaj  

Proposed design procedure for transmission shafting under fatigue loading [PDF]

A new standard for the design of transmission shafting is reported. Computed was the diameter of rotating solid steel shafts under combined cyclic bending and steady torsion is presented.
Loewenthal, S. H.
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Effect of Lactobacillus acidophilus XY27 in Regulating Intestinal Flora and Enhancing Swimming Endurance

Shipin gongye ke-ji
This study investigated the effects and potential mechanisms of Lactobacillus acidophilus XY27 (LAXY27) on enhancing exercise endurance in mice.
Yanwei ZONG, Canlin SONG, Dehan LUO, Chenxi JIAO   +3 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Cluster analysis as an effective tool for identifying physical fitness in students: the basis for an innovative approach to optimizing physical education in the university environment

Frontiers in Physiology
ObjectiveThis study analyzes university students’ physical fitness and, based on the results, applies cluster analysis to identify homogeneous groups with aim to optimize physical education programs at the university.MethodsA group of 88 first-year ...
Alena Cepková, Richard Cepka, Ľubomír Šooš, Oto Honz, Marián Uvaček, Ján Žiška, Erika Zemková   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source