Results 121 to 130 of about 549,229 (283)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Investigation of cavitation damage of a mechanical pump impeller in high temperature potassium quarterly progress report no. 1, 7 dec. 1964 - 28 feb. 1965 [PDF]
Cavitation damage prediction from mixed flow centrifugal pump impeller in endurance testing in high temperature ...
Altieri, J. V., Kulp, R. S.
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
European Journal of Sport ScienceThis study aimed to investigate the effects of an 8‐week lat pull‐down resistance training program with joint instability on pull‐up performance in male college students.
Qian Li +7 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
European Journal of Sport ScienceCurrent guidelines for prolonged altitude exposure suggest altitude levels ranging from 2000 to 2500 m to optimize an increase in total hemoglobin mass (Hbmass). However, natural low altitude locations (
Bastien Krumm +8 more
doaj +1 more source
The Comparison of Motoric Characteristics of Young Soccer Players According to Their Playing Positions [PDF]
Sportif Bakış Spor ve Eğitim Bilimleri Dergisi, 2016 The purpose of this study was to compare motoric features, 10-30m speed, agility, flexibility, standing long jump and yo-yo 1 test according to playing position at young soccer players.
Ayşegül Yapıcı +3 more
doaj
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Shipin gongye ke-jiThis study investigated the effects and potential mechanisms of Lactobacillus acidophilus XY27 (LAXY27) on enhancing exercise endurance in mice.
Yanwei ZONG +3 more
doaj +1 more source