Results 81 to 90 of about 5,733,113 (297)

Developments in additive manufacturing of energetic materials at TNO

, 2017
Since common energetic materials are not easily compatible with existing additive manufacturing techniques, the Energetic Materials department of TNO in the Netherlands worked closely together with the Additive Manufacturing and Material Solutions groups
Lingen, J.N.J. van, Straathof, M.H., Driel, C.A. van   +2 more
core  

Observation of Enhanced Radial Transport of Energetic Ion due to Energetic Particle Mode Destabilized by Helically-trapped Energetic Ion in the Large Helical Device [PDF]

, 2018
0000-0003-4555-1837A deuterium experiment was initiated to achieve higher-temperature and higher-density plasmas in March 2017 in the Large Helical Device (LHD).
SEKI, Ryosuke, LHD Experiment Group,, OSAKABE, Masaki, The LHD Experiment Group,, OGAWA, Kunihoro, ISOBE, Mitsutaka, Nishitani, T., Kawase, Hiroki   +7 more
core   +2 more sources

Ti/CuO Nanothermite—Study of the Combustion Process

Molecules
A study of the combustion processes of Ti/CuO and Ti/CuO/NC nanothermites prepared via electrospraying was conducted in this work. For this purpose, the compositions were thermally conditioned at 350, 550 and 750 °C, as selected based on our initial ...
Mateusz Polis, Konrad Szydło, Barbara Lisiecka, Marcin Procek, Tomasz Gołofit, Tomasz Jarosz, Łukasz Hawełek, Agnieszka Stolarczyk   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Synthesis and properties of random co-polymer poly-(GA/BAMO) as energetic binder

, 2015
101.1101.14Random copolymer with monomer units from glycidyl azide (GA) and 3,3-bisazidomethyloxetane (BAMO) has been synthesized to produce a material for potential application as energetic binder for solid rocket propellant.
Janitschek, Wieland, Krause, Horst, Schaller, Uwe, Kaiser, Manfred, Keicher, Thomas   +4 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Research on the synthesis and properties of 2,4,6,8-Tetranitro naphthalene-1,5-diol and its three salts

Results in Chemistry
2,4,6,8-tetranitronaphthalene-1,5-diol (4) and its three nitrogen-containing salts were synthesized. These energetic compounds were synthesized and characterized for the first time using multi-nuclear magnetic resonance spectroscopy, elemental analysis ...
Xingcheng zhang, Saipei Guo, Lianghan Shi, Wenxiang Hu, Qiuju zhou, Lingyun Zheng   +5 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Study on Full-Size Drop Impact Response Characteristics and Safety of Marine Equipment

水下无人系统学报
The drop safety of marine equipment is of paramount importance in daily operational tasks. To assess the safety of a full-size drop of a certain type of equipment, a finite element simulation model of the overall structure was established using LS-DYNA ...
Tingting WANG, Yongfu SHEN, Junli MA, Gangling JIAO, Jian ZHANG, Yawei WANG   +5 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source