Results 111 to 120 of about 14,999,670 (363)
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
2009 Annual Report to Congress [PDF]
[Excerpt] Enacted in 2004, Public Law 108-375 also created an Office of the Ombudsman (the Office) and urged the Secretary of Labor to take appropriate action to ensure that it be an independent Office within the Department of Labor (DOL), including ...
Ombudsman of the Energy Employees Occupational Illness Compensation Program, Part E
core +1 more source
International Transactions on Electrical Energy Systems
doaj +1 more source
Relating Energy and Sombor Energy
Ivan Gutman +2 more
openaire +2 more sources
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
2012 Annual Report to Congress [PDF]
[Excerpt] Public Law 108-375 not only repealed Part D and established Part E it also created the Office of the Ombudsman (the Office). The law urged the Secretary to ensure the independence of the Office within DOL, including independence from other ...
Ombudsman of the Energy Employees Occupational Illness Compensation Program, Part E
core +1 more source
Retracted: Application of Wireless Sensor Network Computer Technology in Financial Management System
International Transactions on Electrical Energy Systems
doaj +1 more source
Acceleration, energy loss and screening in strongly-coupled gauge theories [PDF]
Mariano Chernicoff, Alberto Güijosa
openalex +1 more source
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source

