Results 111 to 120 of about 14,999,670 (363)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

2009 Annual Report to Congress [PDF]

open access: yes, 2010
[Excerpt] Enacted in 2004, Public Law 108-375 also created an Office of the Ombudsman (the Office) and urged the Secretary of Labor to take appropriate action to ensure that it be an independent Office within the Department of Labor (DOL), including ...
Ombudsman of the Energy Employees Occupational Illness Compensation Program, Part E
core   +1 more source

Retracted: Feasibility Deconstruction on the Establishment of Martial Arts Short Soldier Course Assisted by Multimedia Computer Network

open access: yesInternational Transactions on Electrical Energy Systems, 2023
International Transactions on Electrical Energy Systems
doaj   +1 more source

Relating Energy and Sombor Energy

open access: yesContributions to Mathematics, 2021
Ivan Gutman   +2 more
openaire   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

2012 Annual Report to Congress [PDF]

open access: yes, 2013
[Excerpt] Public Law 108-375 not only repealed Part D and established Part E it also created the Office of the Ombudsman (the Office). The law urged the Secretary to ensure the independence of the Office within DOL, including independence from other ...
Ombudsman of the Energy Employees Occupational Illness Compensation Program, Part E
core   +1 more source

Retracted: Application of Wireless Sensor Network Computer Technology in Financial Management System

open access: yesInternational Transactions on Electrical Energy Systems, 2023
International Transactions on Electrical Energy Systems
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

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