Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Safety Impact resistance is defined as the ability of a material to absorb impact energy through a controlled failure mechanism. The greater the energy absorption by the crash safety structure, the greater the safety in preventing deformation of the main
Andre Hartawan Mettanadi +4 more
doaj +1 more source
Thermal Parameters Calibration and Energy-Saving Evaluation of Spectral Selective Absorption Film Coated Glazing System Based on Heat Transfer Simulation [PDF]
Xu Chen, Saihong Zhu, Tianyi Chen
openalex +1 more source
Spectroscopic evidences of quantum critical charge fluctuations in cuprates
We calculate the optical conductivity in a clean system of quasiparticles coupled to charge-ordering collective modes. The absorption induced by these modes may produce an anomalous frequency and temperature dependence of low-energy optical absorption in
Abanov +17 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Research into energy absorption of liquid cabin subjected to close-range explosion
In order to study the energy absorption of different parts of a liquid cabin under a close-range explosion, a fluid-structure coupling model is built on the basis of experiments, and the deformation of the bulkhead and energy absorption ratio of ...
LI Siyu +3 more
doaj +1 more source
Investigation of Impulse Aging of Energy-Absorption Elements for Hybrid DC Circuit Breakers [PDF]
Xinyi Wang +6 more
openalex +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Ultrahigh Energy Absorption Multifunctional Spinodal Nanoarchitectures
AbstractNanolattices are promoted as next‐generation multifunctional high‐performance materials, but their mechanical response is limited to extreme strength yet brittleness, or extreme deformability but low strength and stiffness. Ideal impact protection systems require high‐stress plateaus over long deformation ranges to maximize energy absorption ...
Anna Guell Izard +4 more
openaire +3 more sources
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source

