Results 51 to 60 of about 607,724 (262)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Provincial Energy Balance Analysis: Karabük Sample

open access: yesGazi Üniversitesi Fen Bilimleri Dergisi, 2017
The purpose of this study; to reveal the energy supply-demand balance of the Karabük province, to evaluate their overall trends and the share of brown and green energy in the balance and to create an energy flowchart.
Seyfi ŞEVİK
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Study of Fire Plume Behavior and Maximum Ceiling Temperature Rise in a Curved Tunnel Driven by the Coupling of Blockage Effect and Longitudinal Ventilation

open access: yesFire
Tunnel fires often lead to vehicles being trapped inside, causing the “blocking effect”. In this work, fire plume behavior and the maximum ceiling temperature rise in a curved tunnel with blocked vehicles under longitudinal ventilation conditions are ...
Xin Zhang   +7 more
doaj   +1 more source

Poland’s Energy Balance in a Long Term Perspective [PDF]

open access: yesActa Montanistica Slovaca, 2006
The basic task of economy is meeting the consumption and development needs of society. This process undergoes dynamic changes as the economical development evolves.
Maciej Kalinski
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Energy balance of irrigated maize silage

open access: yesCiência Rural, 2018
: The aim of the present study is to evaluate the energy balance and energy efficiency of the silage maize crop in the Center for Research, Development and Technology Transfer of the Universidade Federal de Lavras (CDTT-UFLA).
Tomás de Aquino Ferreira   +6 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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