Results 61 to 70 of about 728,565 (310)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Evaluation of the Surface Energy Balance System (SEBS) applied to ASTER imagery with flux-measurements at the SPARC 2004 site (Barrax, Spain) [PDF]

, 2009
Accurate quantification of the amount and spatial variation of evapotranspiration is important in a wide range of disciplines. Remote sensing based surface energy balance models have been developed to estimate turbulent surface energy fluxes at different
A. Gieske, van der Kwast, J., Z. Su, Elbers, J., S. de Jong, de Jong, Steven, Sub FG Externen, Timmermans, W., Jong, S., de, Elbers, J.A., Jia, L., Gieske, A.S.M., J. Elbers, Olioso, A., Gieske, A., D. Karssenberg, Timmermans, W.J., W. Timmermans, J. van der Kwast, L. Jia, Landdegradatie en aardobservatie, Su, Z., Olioso, Albert, Kwast, J., van der, de Jong, S., Landscape functioning, Geocomputation and Hydrology, Su, Z.; id_orcid, TIMMERMANS, Antonius, A. Olioso, Karssenberg, D.   +29 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Energy balance of the Earth’s tectonosphere

Геофизический журнал, 2015
Concentration of K, U and Th has been investigated in the rocks of the Earth’s crust and upper mantle of platforms, geosynclines and oceans. The coinsidence has been found between total modern heat emanation in the crust and upper mantle of three types ...
V. Gordienko
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Provincial Energy Balance Analysis: Karabük Sample

Gazi Üniversitesi Fen Bilimleri Dergisi, 2017
The purpose of this study; to reveal the energy supply-demand balance of the Karabük province, to evaluate their overall trends and the share of brown and green energy in the balance and to create an energy flowchart.
Seyfi ŞEVİK
doaj   +1 more source

Verification Of Energy Balance In The Ansys V5.4 Thermal Calculations [PDF]

, 2001
The objective of this calculation is to verify the energy balance of the thermal calculations analyzed by ANSYS Version (V) 5.4 solver (see Section 4).
Marr, H., Anderson, M. J.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source