Results 81 to 90 of about 7,358,194 (305)

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

On the determination of the spatial energy balance of a megacity on the example of Cairo, Egypt [PDF]

, 2010
This research deals with different aspects of the spatial urban energy balance on the example of the megacity Cairo, Egypt. The energy balance and its single terms were measured in situ during a field campaign in Cairo at three different locations (urban,
Frey, Corinne Myrtha
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

The Energy Balance of Corn Ethanol: An Update [PDF]

Studies conducted since the late 1970s have estimated the net energy value (NEV) of corn ethanol. However, variations in data and assumptions used among the studies have resulted in a wide range of estimates.
Duffield, James A., Shapouri, Hosein, Wang, Michael Q.   +2 more
core  

Evaluation of the Surface Energy Balance System (SEBS) applied to ASTER imagery with flux-measurements at the SPARC 2004 site (Barrax, Spain) [PDF]

, 2009
Accurate quantification of the amount and spatial variation of evapotranspiration is important in a wide range of disciplines. Remote sensing based surface energy balance models have been developed to estimate turbulent surface energy fluxes at different
A. Gieske, van der Kwast, J., Z. Su, Elbers, J., S. de Jong, de Jong, Steven, Sub FG Externen, Timmermans, W., Jong, S., de, Elbers, J.A., Jia, L., Gieske, A.S.M., J. Elbers, Olioso, A., Gieske, A., D. Karssenberg, Timmermans, W.J., W. Timmermans, J. van der Kwast, L. Jia, Landdegradatie en aardobservatie, Su, Z., Olioso, Albert, Kwast, J., van der, de Jong, S., Landscape functioning, Geocomputation and Hydrology, Su, Z.; id_orcid, TIMMERMANS, Antonius, A. Olioso, Karssenberg, D.   +29 more
core   +4 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dynamic Energy Balance and Obesity Prevention

Journal of Obesity & Metabolic Syndrome, 2018
Dynamic energy balance can give clinicians important answers for why obesity is so resistant to control. When food intake is reduced for weight control, all components of energy expenditure change, including metabolic rate at rest (resting energy ...
Sunmi Yoo
doaj   +1 more source