Results 41 to 50 of about 941,733 (298)

Multi-energy calibration applied to atomic spectrometry [PDF]

Analytica Chimica Acta, 2017
Multi-energy calibration (MEC) is a novel strategy that explores the capacity of several analytes of generating analytical signals at many different wavelengths (transition energies). Contrasting with traditional methods, which employ a fixed transition energy and different analyte concentrations to build a calibration plot, MEC uses a fixed analyte ...
Alex Virgilio, Daniel A. Gonçalves, Tina McSweeney, José A. Gomes Neto, Joaquim A. Nóbrega, George L. Donati   +5 more
openaire   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Signal yields, energy resolution, and recombination fluctuations in liquid xenon [PDF]

, 2016
This work presents an analysis of monoenergetic electronic recoil peaks in the dark-matter-search and calibration data from the first underground science run of the Large Underground Xenon (LUX) detector.
Akerib, D. S., Alsum, S., Araújo, H. M., Bai, X., Bailey, A. J., Balajthy, J., Beltrame, P., Bernard, E. P., Bernstein, A., Biesiadzinski, T. P., Boulton, E. M., Bramante, R., Brás, P., Byram, D., Cahn, S. B., Carmona-Benitez, M. C., Chan, C., Chiller, A. A., Chiller, C., Currie, A., Cutter, J. E., Davison, T. J. R., Dobi, A., Dobson, J. E. Y., Druszkiewicz, E., Edwards, B. N., Faham, C. H., Fiorucci, S., Gaitskell, R. J., Gehman, V. M., Ghag, C., Gibson, K. R., Gilchriese, M. G. D., Hall, C. R., Hanhardt, M., Haselschwardt, S. J., Hertel, S. A., Hogan, D. P., Horn, M., Huang, D. Q., Ignarra, C. M., Ihm, M., Jacobsen, R. G., Ji, W., Kamdin, K., Kazkaz, K., Khaitan, D., Knoche, R., Larsen, N. A., Lee, C., Lenardo, B. G., Lesko, K. T., Lindote, A., Lopes, M. I., Manalaysay, A., Mannino, R. L., Marzioni, M. F., McKinsey, D. N., Mei, D. -M., Mock, J., Moongweluwan, M., Morad, J. A., Murphy, A. St. J., Nehrkorn, C., Nelson, H. N., Neves, F., O'Sullivan, K., Oliver-Mallory, K. C., Palladino, K. J., Pease, E. K., Phelps, P., Reichhart, L., Rhyne, C., Shaw, S., Shutt, T. A., Silva, C., Solmaz, M., Solovov, V. N., Sorensen, P., Stephenson, S., Sumner, T. J., Szydagis, M., Taylor, D. J., Taylor, W. C., Tennyson, B. P., Terman, P. A., Tiedt, D. R., To, W. H., Tripathi, M., Tvrznikova, L., Uvarov, S., Verbus, J. R., Webb, R. C., White, J. T., Whitis, T. J., Witherell, M. S., Wolfs, F. L. H., Xu, J., Yazdani, K., Young, S. K., Zhang, C.   +100 more
core   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Development of a method for measuring low energy electron beam irradiation parameters by calorimetry and step stacking

Fushe yanjiu yu fushe gongyi xuebao
Electron beam irradiation processing has become an important component of the nuclear technology industry, with low-energy electron beam increasingly being applied in processes such as coating curing, wastewater treatment, and food preservation. Accurate
LUO Rui, ZHANG Yuhe, MAO Naqing
doaj   +1 more source

Summary of the 13th IACHEC Meeting [PDF]

, 2019
We summarize the outcome of the 13th meeting of the International Astronomical Consortium for High Energy Calibration (IACHEC), held at Tenuta dei Ciclamini (Avigliano Umbro, Italy) in April 2018. Fifty-one scientists directly involved in the calibration
Belanger, G., Grant, C. E., Guainazzi, M., Kashyap, V., Madsen, K. K., Marshall, H. L., Miller, E. D., Natalucci, L., Nevalainen, J., Plucinsky, P. P., Terada, Y.   +10 more
core   +1 more source

Astrometric calibration and performance of the Dark Energy Camera [PDF]

, 2017
We characterize the ability of the Dark Energy Camera (DECam) to perform relative astrometry across its 500~Mpix, 3 deg^2 science field of view, and across 4 years of operation.
A. A. Plazas, A. Benoit-Lévy, A. Carnero Rosell, A. R. Walker, A. Roodman, C. E. Cunha, D. Brooks, D. Gruen, D. J. James, D. L. Burke, D. L. DePoy, D. W. Gerdes, E. Fernandez, E. Krause, E. S. Rykoff, E. Sanchez, E. Suchyta, F. Menanteau, F. Sobreira, G. Gutierrez, G. M. Bernstein, G. Tarle, H. T. Diehl, I. Sevilla-Noarbe, J. Carretero, J. Frieman, J. García-Bellido, J. Gschwend, J. L. Marshall, K. Bechtol, K. Honscheid, K. Kuehn, K. Reil, L. N. da Costa, M. A. G. Maia, M. Carrasco Kind, M. E. C. Swanson, M. March, M. Schubnell, M. Smith, M. Soares-Santos, N. Kuropatkin, null null, P. Fosalba, R. A. Gruendl, R. Armstrong, R. C. Smith, R. L. C. Ogando, R. Miquel, R. Schindler, S. Allam, S. Desai, S. Kent, T. F. Eifler, T. M. C. Abbott, T. S. Li, V. Scarpine   +56 more
core   +3 more sources

Validation of Calibrated Energy Models: Common Errors [PDF]

Energies, 2017
Nowadays, there is growing interest in all the smart technologies that provide us with information and knowledge about the human environment. In the energy field, thanks to the amount of data received from smart meters and devices and the progress made in both energy software and computers, the quality of energy models is gradually improving and, hence,
Germán Ruiz, Carlos Bandera
openaire   +3 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Design and Preliminary Property Research of Double-Grid Ionization Chamber for CSNS Back-n White Neutron Source

Journal of Isotopes, 2022
A double-grid ionization chamber(GIC) based on the 10B(n,α)7Li and 6Li(n,α)T nuclear reaction has been developed for neutron energy spectrum measurement in the energy region below 150 keV of CSNS/Back-n by time of flight method.
HE Yuyang;LIU Yuntao;LIU Yina;WANG Zhiqiang;LI Chunjuan;XIA Li;LUO Hailong
doaj