Results 101 to 110 of about 8,722,657 (381)
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Oxygen Activation and Energy Conservation by Cytochrome c Oxidase
This review focuses on the type A cytochrome c oxidases (CcO), which are found in all mitochondria and also in several aerobic bacteria. CcO catalyzes the respiratory reduction of dioxygen (O2) to water by an intriguing mechanism, the details of which ...
M. Wikström, K. Krab, Vivek Sharma
semanticscholar +1 more source
Cross-Scale Simulation Study of Porous Medium Heat Exchangers Based on Reliable Cell Selection
This study compares the heat transfer and pressure drop of three cell structures, namely Kelvin cells (KCs), ellipsoidal Kelvin cells (EKCs), and body-centered cubic (BCC) structures, at the cell scale in order to identify the superior configuration ...
Yiqiang Liang +4 more
doaj +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Developments and challenges in hydrate-based carbon dioxide sequestration technology
Hydrate-based carbon dioxide (CO2) sequestration (HBCS) technology utilizes naturally occurring high-pressure and low-temperature marine conditions to convert CO2 into solid hydrates within marine sediments, offering a promising complementary pathway for
Yingying Liu +7 more
doaj +1 more source
During solar cell operation, most light energy converts to heat, raising the battery temperature and reducing photoelectric conversion efficiency. Thus, lowering the temperature of solar cells is essential.
Hui Liu +4 more
doaj +1 more source
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source

