Results 81 to 90 of about 8,610,041 (309)
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
International Journal of Renewable Energy DevelopmentMicrogrid systems are part of the most reliable energy supply technologies for rural communities that do not have access to electricity but the system is generally dominated by diesel generators (DG).
Adinda Prawitasari +8 more
doaj +1 more source
On energy-momentum conservation
Physics Letters B, 1984 Abstract In this note I show how to use the replicas formalism to study the macroscopic consequences of a random violation of energy-momentum conservation at the microscopic level (i.e. at distances much smaller than 10 −13 cm).
openaire +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Creep Behaviors of Methane Hydrate-Bearing Frozen Sediments
Energies, 2019 Creep behaviors of methane hydrate-bearing frozen specimens are important to predict the long-term stability of the hydrate-bearing layers in Arctic and permafrost regions.
Yanghui Li +5 more
doaj +1 more source
Energy Conservation via Hydrogen Cycling in the Methanogenic Archaeon Methanosarcina barkeri
mBio, 2018 Energy conservation via hydrogen cycling, which generates proton motive force by intracellular H2 production coupled to extracellular consumption, has been controversial since it was first proposed in 1981.
G. Kulkarni, Thomas D. Mand, W. Metcalf
semanticscholar +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Experimental Study of Spray Characteristics of Kerosene-Ethanol Blends from a Pressure-Swirl Nozzle
International Journal of Aerospace Engineering, 2018 Partial replacement of kerosene by ethanol in a gas turbine is regarded as a good way to improve the spray quality and reduce the fossil energy consumption.
Tao Zhang +5 more
doaj +1 more source