Results 41 to 50 of about 6,610,346 (266)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

A hydrate blockage detection apparatus for gas pipeline using ultrasonic focused transducer and its application on a flow loop

open access: yesEnergy Science & Engineering, 2020
This paper introduces a novel apparatus and the analyzing method for hydrate blockage detection in natural gas pipeline using the ultrasonic focused testing technique.
Xingbo Li   +6 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Pore‐Scale Intermittent Flow and Its Impact on Two‐Phase Fluid Distribution in Porous Media

open access: yesWater Resources Research
Understanding two‐phase flow in porous media is essential for optimizing subsurface storage efficiency. Pore‐scale flow properties significantly influence macroscopic plume migration behavior and trapping performance.
Xin Wang   +9 more
doaj   +1 more source

Application of chemiresistive sensors based on the metal-organic framework for detecting volatile organic compounds

open access: yes工程科学学报, 2022
Chemical resistance sensors stand out among many gas sensing methods because of their simple structure, low-cost fabrication, facile integration with various electronic devices, and quick analysis; therefore, presently, they are widely used for gas ...
Ben NIU   +4 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Effect of confining pressure on mechanical behavior of methane hydrate-bearing sediments

open access: yesPetroleum Exploration and Development, 2011
Synthesized gas hydrate in lab was mixed with kaoline to form core samples, so as to simulate the hydrate-bearing sedimentary layers in the seabed. Under conditions of different confining pressure, triaxial compressive tests were conducted on hydrate ...
Yanghui Li   +4 more
doaj   +1 more source

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