Results 41 to 50 of about 7,477,471 (308)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Energy, Sustainability and SocietyBackground Sufficiency is a critical but often overlooked decarbonization strategy. A significant challenge in promoting sufficiency is the difficulty in assessing its social co-benefits, such as improved health outcomes.
Jens Teubler, Malte Neumann
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Decreasing Ore Grades in Global Metallic Mining: A Theoretical Issue or a Global Reality?
Resources, 2016 Mining industry requires high amounts of energy to extract and process resources, including a variety of concentration and refining processes.
Guiomar Calvo +3 more
doaj +1 more source
Three-dimensional numerical simulation of heat transfer and flow of waxy crude oil in inclined pipe
Case Studies in Thermal Engineering, 2022 The purpose of this study is to obtain the heat transfer and flow law of waxy crude oil in the inclined pipeline and to provide theoretical guidance for the safe operation of the pipeline.
Lianjie Zhang +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Simulation of Iran's Energy Balance and Designing Supply and Demand Management Scenarios for 2042 Using LEAP [PDF]
Pizhūhishnāmah-i Iqtiṣād-i Inirzhī-i Īrān, 2018 Importance of long-term planning in the energy sector and employing policy design tools are focal and strategic issues of the country. The main objective of this paper is to measure the supply (Energy Transformation) and demand of energy during the ...
Shaker Mohammadi +3 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source