Results 51 to 60 of about 7,477,471 (308)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Energy Consumption and Economic Growth：Evidence from 5 Asian Countries

, 2013
2013-09-30This paper investigates the causal relationship between nuclear energy consumption, renewable energy and oil consumption, natural gas consumption, coal consumption and economic growth for 5 Asian countries: China, India, Japan, Pakistan and ...
DONG, Weijia, WU, Jingyi, LV, Xin
core   +1 more source

SOFIAS – Herramienta para el análisis de ciclo de vida y la calificación ambiental de edificios

Informes de la Construccion, 2016
Este artículo describe el proceso de desarrollo de la nueva herramienta informática SOFIAS (Software de Funciones Integradas para una Arquitectura Sostenible), financiado por el Ministerio de Economía y Competitividad del Gobierno de España.
X. Oregi Isasi, J. A. Tenorio, C. Gazulla, I. Zabalza, D. Cambra, S. O. Leao, L. Mabe, S. Otero, J. Raigosa   +8 more
doaj   +1 more source

Fossil Fuel and Biofuel Boilers in Ukraine: Trends of Changes in Levelized Cost of Heat

Energies, 2022
An increase in the share of renewables in heat supply systems is a promising direction to reach sustainable development goals and decarbonization. Decision makers should consider various factors, including energy market prices, the availability of ...
Valentyna Stanytsina, Volodymyr Artemchuk, Olga Bogoslavska, Artur Zaporozhets, Antonina Kalinichenko, Jan Stebila, Valerii Havrysh, Dariusz Suszanowicz   +7 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Energy consumption characteristics of turn-mill machining

, 2017
Reducing the energy consumption of manufacturing processes and machine tools can considerably affect the environmental and economic impact of industrial activities. Since the 2008 global financial crisis, many scholars have focused on modeling the energy
Ünver, Hakkı Özgür, ÜNVER, HAKKI ÖZGÜR, Moradnazhad, Mariyeh   +2 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Multiple-Criteria Decision Analysis and characterisation of phase change materials for waste heat recovery at high temperature for sustainable energy-intensive industry

Materials & Design, 2020
A latent heat storage system based on Phase Change Materials (PCMs) is proposed to increase the energy and environmental efficiency by recovering and storing waste heat from combustion gases or other surplus sources at in the energy-intensive industries (
Patricia Royo, Victor J. Ferreira, Zafer Ure, Sam Gledhill, Ana M. López-Sabirón, Germán Ferreira   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source