Results 51 to 60 of about 2,539,572 (302)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Simulation of Iran's Energy Balance and Designing Supply and Demand Management Scenarios for 2042 Using LEAP [PDF]

Pizhūhishnāmah-i Iqtiṣād-i Inirzhī-i Īrān, 2018
Importance of long-term planning in the energy sector and employing policy design tools are focal and strategic issues of the country. The main objective of this paper is to measure the supply (Energy Transformation) and demand of energy during the ...
Shaker Mohammadi, Ali Emami Meibodi, Afshin Javan, Amir Hossein Fakehi   +3 more
doaj   +1 more source

Gatekeepers changing consumers' behaviour in energy consumption [PDF]

, 2009
Changing people's behaviour and reducing energy consumption has proved to be more difficult than attitudes or technical possibilities would imply. In this paper we discuss how to intervene the individual decisions that significantly determine energy ...
Kaskinen, Tuuli, Kuittinen, Outi, Mokka, Roope, Neuvonen, Aleksi   +3 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Multi-utility service companies: a complex systems model of increasing resource efficiency [PDF]

, 2015
Domestic households account for a significant portion of energy consumption and carbon emissions in the United Kingdom. Gains in energy and resource efficiency are undermined by the continuing rise in consumption.
Allen, Peter, Robinson, Marguerite, Varga, Liz   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

SOFIAS – Herramienta para el análisis de ciclo de vida y la calificación ambiental de edificios

Informes de la Construccion, 2016
Este artículo describe el proceso de desarrollo de la nueva herramienta informática SOFIAS (Software de Funciones Integradas para una Arquitectura Sostenible), financiado por el Ministerio de Economía y Competitividad del Gobierno de España.
X. Oregi Isasi, J. A. Tenorio, C. Gazulla, I. Zabalza, D. Cambra, S. O. Leao, L. Mabe, S. Otero, J. Raigosa   +8 more
doaj   +1 more source

Fossil Fuel and Biofuel Boilers in Ukraine: Trends of Changes in Levelized Cost of Heat

Energies, 2022
An increase in the share of renewables in heat supply systems is a promising direction to reach sustainable development goals and decarbonization. Decision makers should consider various factors, including energy market prices, the availability of ...
Valentyna Stanytsina, Volodymyr Artemchuk, Olga Bogoslavska, Artur Zaporozhets, Antonina Kalinichenko, Jan Stebila, Valerii Havrysh, Dariusz Suszanowicz   +7 more
doaj   +1 more source